A-Calm 50

Generic

Tolperisone Hydrochloride

Indications

Increased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis etc.), muscular hypertension, muscular spasm, muscular contraction & rigidity, spinal automatism and discopathy. Obliterate vascular diseases (obliterate arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, raynaud's disease, diffusion scleroderma) and disorders due to injury innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases post thrombotic venous and circulation disorders and crural ulcer.

Pharmacology

Tolperisone Hydrochloride is a centrally acting muscle relaxant that acts on the central nervous system and is used to treat high muscular tone and stress, as well as certain circulation issues in the extremities.

Dosage & Administration 

The recommended dose is as follows:

• Adult: 50-150 mg three times daily according to the individual requirement and tolerance of the patient.
• Children (from 3 months to 6 years): 5 mg/kg/day in three divided doses.
• Children (from 6 to 14 years): 2-4 mg/kg/day in three divided doses. or, as directed by the registered physician.

Interaction

The usage of methocarbamol and Tolperisone Hydrochloride together has been linked to visual accommodation problems.

Contraindications

Patients having a history of hypersensitivity to any component of the product, myasthenia gravis, and nursing mothers should avoid it.

Side Effects

Muscle weakness, headache, nausea, and vomiting are all possible side effects, while hypersensitivity reactions (itching, redness, and skin rash) are rare.

Pregnancy & Lactation

Tolperisone hydrochloride should be used in pregnancy to physician's advice. Tolperisone hydrochloride should not be used during breast-feeding.

Precautions & Warnings

Incase of children, the prescribed dose and duration of treatment should closely be observed.

Therapeutic Class

Storage Conditions

Pharmaceutical Name

ACME Laboratories Ltd.