Betapro 5

Indications of Betapro 5 Tablet

Bisoprolol is suitable for -

Hypertension,  Angina pectoris , Moderate to severe heart failure

 

Pharmacology of Betapro 5 Tablet

Bisoprolol hemifumarate is the most selective ß1 blocker. Compared to any other beta-blocker available to date, it has the highest affinity for ß1 receptors. It selectively blocks β1 adrenergic receptors in the heart and vascular smooth muscle, reduces heart rate and cardiac output, resulting in a reduction in arterial hypertension .In patients using non-selective β1 blockers, β blockers may have an adverse effect on lipid metabolism, but bisoprolol will not cause any change in cholesterol during long-term treatment, including cardioprotective HDL cholesterol.

 

Dosage & Administration of Betapro 5 Tablet

Hypertension:  The dosage of bisoprolol should be individualized according to the needs of the patient. The usual starting dose is 5 mg once a day. In some patients, 2.5 mg may be a suitable starting dose. If the hypotensive effect of 5 mg is insufficient, the dose can be increased to 10 mg and then, if necessary, to , to 20 mg once daily. 

Angina:  generally 10 mg per day (5 mg may be sufficient for some patients), up to 20 mg per day. 

Heart failure:  initially 1.25 mg once daily (morning) for 1 week, then, if well tolerated, increase to 2.5 mg once daily for 1 week, then to 3.75 mg once a day for 1 week, then 5 mg a day, for 4 weeks, then 7.5 mg once a day for 4 weeks, then 10 mg once a day, up to 10 mg a day.

 

Interaction of Betapro 5 Tablet

Bisoprolol should not be combined with other beta blockers.

 

Contraindications

In patients with cardiogenic shock, obvious heart failure, second or third degree atrioventricular block, right ventricular failure secondary to pulmonary hypertension , and sinus bradycardia.

 

Side-Effects of Betapro 5 Tablet

There may be gastrointestinal disorders, bradycardia, hypotension, headache, fatigue, sleep disturbance, dizziness, dizziness, thrombocytopenia, visual disturbance, and hair loss.

 

Pregnancy & Lactation

The safety of bisoprolol during pregnancy has not been established. There are no data on breastfeeding.

 

Precautions & Warnings

During long-term treatment with bisoprolol, kidney, liver and hematopoietic functions should be monitored regularly.

 

Therapeutic Class

Anti adrenergic agent (Beta blockers),Beta-adrenoceptor blocking drugs,Beta-blockers

 

Storage Conditions

Store in a dry place away from light and heat. Keep out of reach of children

 

Pharmaceutical Name of Betapro 5 Tablet

Beximco Pharmaceuticals Ltd

 

Generic of Betapro 5 Tablet

Bisoprolol Hemifumarate