The recommended dose of Empagliflozin is 10 mg once daily, taken in the morning, with or without food. In patients tolerating Empagliflozin, the dose may be increased to 25 mg once daily. In patients with volume depletion, correcting this condition prior to initiation of Empagliflozin is recommended.
Diuretics: Enpagliflozin combined with diuretics causes an increase in urine production.
Insulin or insulin secretagogue: Enpagliflozin combined with insulin or insulin secretagogue may increase the risk of hypoglycemia.
Positive urine glucose test: It is not recommended to monitor blood glucose control through a urine glucose test in patients taking SGLT2 inhibitors, because SGLT2 inhibitors increase urine glucose excretion and result in a positive urine glucose test result. Use alternative methods to control blood sugar control.
Interferes with the 1.5 anhydroglucitol (1.5AG) test: The 1.5AG test is not recommended for monitoring blood glucose control because the 1.5AG measurement is not reliable when assessing glucose control in blood in patients taking SGLT2 inhibitors. Use alternative methods to control blood sugar control.
Empagliflozin is contraindicated in patients with a history of severe hypersensitivity, severe renal impairment, end-stage renal disease or dialysis to Empagliflozin or any of its components.
The most common adverse reactions associated with empagliflozin are urinary tract infections and female genital fungal infections. Other common side effects include dehydration, low blood pressure, weakness, dizziness, and increased thirst.
There are no adequate and well-controlled studies of empagliflozin in pregnant women. Empagliflozin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not clear whether empagliflozin is excreted in human milk. its use is not recommended during lactation.
It is recommended to regularly assess renal function before and after starting to use empagliflozin. Empagliflozin should not be started for patients with eGFR lower than 45 ml / min / 1.73 m2. Patients with eGFR greater than or equal to 45 ml/min/1.73 m2 do not need to adjust the dose.
Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Keep in a cool & dry place (below 30° C), protected from light & moisture. Keep out of the reach of children.
Pharmaceuticals name of Empazin 10 Tablet
Delta Pharmaceuticals Ltd
Generic of Empazin 10 Tablet