Indications of Furotil 500
It is shown for the treatment of diseases caused by touchy bacteria.
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes. Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase creating strains) or Streptococcus pyogenes.
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase creating strains)
- Lower respiratory tract diseases counting pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (counting beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli.
- Acute bacterial compounding of incessant bronchitis and auxiliary bacterial contaminations of Intense bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains).
- Uncomplicated skin and skin-structure contaminations caused by Staphylococcus aureus (counting beta-lactamase creating strains) or Streptococcus pyogenes.
-
Uncomplicated urinary tract diseases caused by E.coli or Klebsiella pneumoniae.
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Bone and Joint Diseases caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains).
-
Uncomplicated Gonorrhea caused by penicillinase-producing and non-penicillinase creating strains of Neisseria gonorrhoeae.
-
Early Lyme Infection (erythema migrans) caused by Borrelia burgdorferi.
- Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (counting ampicillin-resistant strains) & Klebsiella spp.
- Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (counting ampicillin-resistant strains), Neisseria meningitidis & Staphylococcus aureus (penicillinase and non-penicillinase creating strains)
- Switch treatment (Injectable to verbal)
Pharmaceutical Name
Healthcare Pharmaceuticals Ltd
Pharmacology
Cefuroxime may be a bactericidal moment era cephalosporin anti-microbial which is dynamic against a wide extend of Gram-positive and Gram-negative vulnerable life forms counting numerous beta-lactamase creating strains. Cefuroxime represses bacterial cell divider amalgamation by interfering with the transpeptidation process.
Clavulanic corrosive may be a normally determined beta lactamase inhibitor delivered by Streptomyces clavuligerus. It has comparative structure to beta lactam anti-microbials which ties irreversibly to beta-lactamase chemicals and inactivates them. Clavulanic corrosive gives security of Cefuroxime from corruption by beta lactamase proteins and gives a arrangement for the treatment of bacterial diseases caused by beta lactam safe microscopic organisms.
Dosage of Furotil 500
Young people and
grown-ups (13
a long time and older)-
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial compounding of constant bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial diseases of intense bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure diseases: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract contaminations: 250 mg b.i.d. for 7-10 days
-
Uncomplicated Gonorrhea: 1000 mg b.i.d. Single dose
-
Community obtained pneumonia: 250-500 mg b.i.d. for 5-10 days
-
MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
-
Early Lyme malady: 500 mg b.i.d. for 20 days
Pediatric Patients (3 months to 12 years)-
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
Administration
Cefuroxime-Clavulanic Corrosive tablet may be taken without respect of nourishment.
Interaction of Furotil 500
Concomitant organization of probenecid with Cefuroxime-Clavulanic Corrosive increments the range beneath the serum concentration versus time bend by 50%. Sedate that decreases gastric corrosiveness may result in a lower bioavailability of Cefuroxime and tend to cancel the impact of postprandial assimilation.
Contraindications
Cefuroxime-Clavulanic Corrosive is contraindicated in patients with known hypersensitivity to cephalosporin & in patients with Pseudomembranous Colitis.
Side Effects of Furotil 500
By and large Cefuroxime-Clavulanic Corrosive is well endured. Be that as it may, some side impacts like sickness, spewing, the runs, stomach distress or torment may happen. As with other broad-spectrum anti-microbials, delayed organization of Cefuroxime and Clavulanic corrosive combination may result in excess of nonsusceptible microorganisms. Once in a while (<0.2%) renal brokenness, anaphylaxis, angioedema, pruritis, hasty and serum affliction like urticaria may show up.
Pregnancy & Lactation
Whereas all anti-microbials ought to be dodged within the to begin with trimester in case conceivable. In any case, Cefuroxime-Clavulanic Corrosive can be securely utilized in afterward pregnancy to treat urinary and other contaminations. Cefuroxime-Clavulanic Corrosive is excreted into the breast drain in little amounts. Be that as it may, the plausibility of sensitizing the newborn child ought to be kept in intellect.
Precautions & Warnings
Cefuroxime ought to be given with care to patients getting concurrent treatment with strong diuretics & who has history of colitis.
Therapeutic Class
Second generation Cephalosporins
Storage Conditions
Store in a cool, dry put (underneath 30o C), absent from light and dampness. Keep out of the reach of children.
Generic Name of Furotil 500
Cefuroxime Axetil
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