Lorfast 10

Generic

Loratadine

 

Indications

Loratadine pill relieves the symptoms of seasonal allergic rhinitis, perennial allergic rhinitis, and skin allergies, including chronic urticaria, quickly and effectively. It also helps to relieve allergic rhinitis symptoms including sneezing, nasal discharge, itching, ocular irritation, and burning. Oral administration relieves nasal and ocular signs and symptoms quickly. Idiopathic urticaria is also treated with loratadine tablets. Loratadine pill is used to treat seasonal allergic rhinitis and allergic skin disorders including urticaria and nettlerash in children over the age of two.

 

Pharmacology

This pill is a Loratadine preparation. Loratadine is an antiallergic histamine Hr receptor antagonist that is non-sedative. Loratadine is a long-acting tricyclic antihistamine with selective peripheral Hi-receptor antagonistic action but no sedative or anticholinergic properties. It works quickly and lasts a long time, allowing for once-daily administration.

 

Dosage & Administration

Adults and children over 12 years of age: One Loratadine tablet once daily. It is usually administered in the morning or when symptoms require treatment.

Children 2-12 years: Body weight over 30 kg: one Loratadine tablet once daily, below 30 kg: half Loratadine tablet once daily.

Below 2 years of age: Loratadine tablet is not recommended for use below 2 years of age since safety and efficacy has not been established.

 

Interaction

There have been no reports of potentially dangerous medication interactions. Loratadine, unlike many other histamine H1 receptor antagonists, has no potentiating effects when combined with alcohol, according to psychomotor performance studies. Concurrent treatment with medicines that inhibit or are processed by hepatic cytochromes P450 3A4 and 2D6 might cause an increase in plasma concentrations of either medication, which can have negative consequences. Both enzymes are inhibited by cimetidine, but P450 3A4 is inhibited by erythromycin or ketoconazole. These medicines raise loratadine levels in the blood, but no side effects have been recorded.

 

Contraindications

Patients who have exhibited hypersensitivity or idiosyncrasy to their components should avoid loratadine.

 

Side Effects

The frequency of adverse events, such as drowsiness and anticholinergic symptoms, reported with 10 mg Loratadine was equivalent to that observed with placebo in controlled clinical investigations. Loratadine's effect on real driving performance, as well as measures of cognitive and psychomotor functioning, has been shown to be equivalent to placebo in studies.

 

Pregnancy & Lactation

There is no evidence that Loratadine has been used in human pregnancy. As a result, it is not recommended for usage during pregnancy. Only a little quantity of loratadine is secreted in breast milk. As a result, it is not recommended that nursing mothers use the medication.

 

Precautions & Warnings

Patients with hepatic disease or renal insufficiency (eGFR 30 ml/min) should exercise caution.

 

Therapeutic Class

Non-sedating antihistamines

 

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

 

Pharmaceutical Name

Biopharma Laboratories Ltd.