Maxbon Kit

Generic

Ibandronic Acid & Calcium Orotate

Indications

This Unit is demonstrated for the treatment and anticipation of osteoporosis in ladies (particularly after menopause) & men. It increments bone mineral thickness (BMD) and decreases the rate of vertebral breaks.

Pharmacology

Sulfadoxine and pyrimethamine are antimalarial drugs that combine the concept of synergy. Compared to the results obtained by combining, the components of the formulation used alone produce lower results at higher doses. In addition, the preparation is effective against strains resistant to other antimalarial drugs, and the risk of the preparation of drug resistance is minimal. It is an extremely long-acting drug that can attack the different developmental stages of parasites, and an effective concentration can be reached with a single administration. The protective effect of a single dose lasts for about 4 weeks, and the preparation is compatible with other antimalarial drugs and antibiotics. It does not affect the effect of antidiabetic drugs.

Dosage & Administration

One tablet of Ibandronic Acid 150 mg once monthly of the same date of each month is recommended. To maximize the clinical benefit of Ibandronic Acid, two tablets of Calcium Orotate per day are usually recommended in divided dosage.

To maximize absorption and clinical benefit, Ibandronic Acid tablet of this Kit should be taken at least 60 minutes before the first food or drink (other than water) of the day or before taking any oral medication or supplementation, including calcium, antacids, or vitamins.

To facilitate delivery to the stomach and thus reduce the potential for esophageal irritation, Ibandronic Acid tablet should be swallowed whole with a full glass of plain water (250 ml) while the patient is standing or sitting in an upright position. Patients should not lie down for 60 minutes after taking Ibandronic Acid tablet.

Ibandronic Acid 150 mg tablet of this Kit should be taken on the same date of each month (i.e., the patients Ibandronic Acid day)

If the once monthly dose is missed, and the patients next scheduled Ibandronic Acid day is more than 7 days away, the patient should be instructed to take one Ibandronic Acid 150 mg tablet in the morning following the date that it is remembered. The patient should then return to taking one Ibandronic Acid 150 mg tablet every month in the morning of their chosen day, according to their original schedule.

If the once monthly dose is missed, and the patients next scheduled Ibandronic Acid day is only 1 to 7 days away, the patient must wait until the subsequent month’s scheduled Ibandronic Acid day to take their tablet. The patient should then return to taking one Ibandronic Acid 150 mg tablet every month in the morning of their chosen day according to their original schedule.

The Patient must not take two Ibandronic Acid 150 mg tablets within the same week.

Start taking Calcium Orotate tablets from the next day of Ibandronic Acid day (from day-2 and onwards).

Interaction

Ibandronic Corrosive: Items containing calcium and other multivalent cautions (such as aluminum, magnesium, press) are likely to meddled with retention of Ibandronic Corrosive. Ibandronic Corrosive ought to be taken at slightest 60 minutes some time recently any verbal solutions. Ibuprofen, NSAIDs, and bisphosphonates are all related with gasrointestinal bothering, caution ought to be worked out within the concomitant utilize of headache medicine of NSNADs with Ibandronic Acid. Calcium Orotate: Calcium can diminish the assimilation of the other drugs such as bisphosphonates (e.g., alendronate/risedronate), quinolone anti-microbials (e.g., ciprofloxacin, levofloxacin), and tetracycline anti-microbial (e.g., doxycycline, levofloxacin).

Contraindications

Ibandronic Corrosive: Anomalies of the esophagus, hypocalcemia, known touchiness to Ibandronic Corrosive or any of its components.

Calcium Orotate: Deficient bowel developments, Kidney stone, Kidney illness and lung malady.

Side Effects

Malacide® at the recommended dose is well tolerated. Main side effects are given belowSkin reactions: Drug rash, pruritus and slight hair loss have been observed. Gastro-intestinal reactions: Feeling of fullness, nausea, rarely vomiting, stomatitis. Haematological reactions: In rare cases, leukopenia, thrombocytopenia, and megaloblastic anemia have been observed. Other reactions: Fatigue, headache, fever, polyneuritis may occasionally occur.

Pregnancy & Lactation

Ibandronic Corrosive: Common side impacts incorporate Hypertension, Dyspepsia, Sickness, The runs, Stomach Torment, Arthralgia, Back Torment, Localized Osteoarthritis, Myalgia, Muscle Spasm, Flu, Nasopharyngitis, Bonchitis, Urinary Tract Disease, Upper Respiratory Tract Disease, Migraine, Discombobulation, Skin Hasty, Sleep deprivation etc.

Calcium Orotate: Bloating and swelling within the guts are common side impacts of Calcium Orotate, misfortune of craving, disturbed stomach, stoppage, sickness, spewing, bizarre weight misfortune, disposit on changes, bone/muscle torment, migraine, expanded thirst/urination, shortcoming, abnormal tiredness, arrangement of kidney stones may happen rarely.

Precautions & Warnings

Ibandronic Acid:

• Ibandronic Acid of this Kit may cause local irritation of the upper gastrointestinal mucosa.
• Adequate intake of Calcium is important in all patient hypocalcaemia
• Severe and occasionally incapacitating bone joint, and/or muscle pain has been reported in patients taking Ibandronic Acid.
• Ibandronic Acid is not recommended for use in patients with severe renal impairment (Creatinine clearance of <30 ml/min).

Calcium Orotate: Before taking Calcium Orotate, precaution is needed if the patient is allergic to Calcium Orotate. Any Calcium supplement taken without food may increase the risk of kidney stones. Therefore, it is advisable that Calcium Orotate be taken with food.

Therapeutic Class

Minerals in bone formation, Specific mineral preparations

Storage Conditions

Pharmaceutical Name

Square Pharmaceuticals Ltd.