MaxD 40000

Generic

Colecalciferol [Vitamin D3]

 

Indications

Vitamin D3 insufficiency can be treated and prevented with MaxD 40000. In patients with vitamin D3 deficiency, it can also be used as a supplement to particular osteoporosis treatment.

 

Pharmacology

MaxD 40000 aids in calcium and phosphorus absorption and reabsorption. Vitamin D3 is required for optimal bone growth and density maintenance. It also helps type 2 diabetes patients maintain optimal insulin levels by reducing the severity of bacterial infection, improving lung function, reducing the risk of cancer (breast, colorectal), and preventing cancer (breast, colorectal).

 

Dosage & Administration

For capsule: Adults:

• Treatment of Vitamin D3 deficiency: 40000 IU once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25 hydroxyvitamin D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.
• Prevention of Vitamin D3 deficiency: 20000 IU every 4 weeks. Higher doses may be required in certain situations.
• Addition to specific therapy for osteoporosis: 20000 IU once a month.

For capsule: Children (12-18 years):

• Treatment of Vitamin D3 deficiency: 20000 IU once every 2 weeks for 6 weeks.
• Prevention of Vitamin D3 deficiency: 20000 IU every 6 weeks.

For film-coated tablets: 1000 IU (1-2 tablets) daily, or as directed by a physician. Take the medicine with food or within 1 hour after a meal.

For oroflash or chewable tablets: 1000 IU to 2000 IU daily, or as directed by a physician. Take the medicine with food or within 1 hour after a meal. Place the tablet in the mouth swallow after chewing.

For Syrup:
For patients with risk of Cholecalciferol deficiency:

• 0-1 yr: 400 IU/ day (2 ml)
• >1 Yr: 600 lU/ day (3 ml)

For Cholecalciferol deficient patients:

• 0-1 yr: 2000 IU/ day (+50000 IU/week ) for 6 weeks
• 1 -18 yrs: 2000 IU/ day for 6 weeks.

Injection: Prevention: 

• Infants receiving Vitamin D enriched milk: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 6 months.
• Nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months.
• Adolescents: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months during winter.
• Pregnancy: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. from the 6th or 7th month of pregnancy.
• Elderly: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 3 months. Digestive disorders, concomitant treatment with antiepileptics & other particular condition not described above; 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. or 1 ampoule (1ml) i.e. 2,00000 I.U. every 3 or 6 months.

Injection: Vitamin D deficiency:

• 1 ampoule (1ml) i.e. 2,00000 I.U. which can be repeated 1 to 6 months later. Or, as directed by the registered physician.

 

Interaction

Phenytoin, barbiturates, glucocorticoids, certain laxatives (such as liquid paraffin), actinomycin, and imidazole antifungal medicines are all affected.

 

Contraindications

Doxophylline is contraindicated in acute myocardial infarction. It is also contraindicated in patients with hypotension, in lactating women & patients who have shown hypersensitivity to its components. It's not recommended for people who have a history of Vitamin D3 hypersensitivity.

 

Side Effects

The general side effects are hypercalcaemia, hypercalciuria, skin rash, pruritus, urticaria, nausea, abdominal pain.

 

Pregnancy & Lactation

Thinks about have appeared secure utilize of measurements up to 4000 IU amid pregnancy. The prescribed day-by-day admissions for pregnant ladies is 400 IU, in any case, in ladies who are considered to be Vitamin D3 insufficient better measurements may be required. During pregnancy, ladies ought to take after the counsel of their therapeutic professional as their prerequisites may change depending on the seriousness of their infection and their reaction to treatment Vitamin D3 and its metabolites are excreted in breast drain. Overdose in newborn children initiated by nursing moms has not been watched; be that as it may, when endorsing extra vitamin D3 to a breastfed child the professional ought to consider the dosage of any extra vitamin D3 given to the mother.

 

Precautions & Warnings

In patients with compromised renal function, it should be used with caution.

 

Therapeutic Class

Vitamin D preparations, vitamin in bone development

 

Storage Conditions

Keep the temperature below 30°C and keep it away from light and moisture. Keep out of children's reach.

 

Pharmaceutical Name

Ziska Pharmaceuticals Ltd.

 

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