Montair 10

Indications

Montair 10 is indicated for:

• Prophylaxis and chronic treatment of asthma
• Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
• Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis.

 

Pharmaceutical Name

Incepta Pharmaceuticals Ltd.

 

Pharmacology

Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) are products of arachidonic acid metabolism and are released from various cells, including mast cells and eosinophils. Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma & allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, which contributes to the signs and symptoms of asthma.

 

Dosage

Adults & adolescents (15 years & older)-

• Asthma & Allergic Rhinitis: 10 mg/day 
• Exercise-Induced Bronchoconstriction: 10 mg/day

Pediatric patients (6 to 14 years)-

• Asthma & Allergic Rhinitis: 5 mg/day 
• Exercise-Induced Bronchoconstriction: 5 mg/day

Pediatric patients (6 months to 5 years)-

• Asthma & Allergic Rhinitis: 4 mg/day 
• Exercise-Induced Bronchoconstriction: Not recommended

Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. For prevention of Acute prevention of Exercise-Induced Bronchoconstriction, a single dose should be taken at least 2 hours before exercise.

 

Administration

Oral administration is the most common route of administration. Montair 10 can be taken with or without food, depending on the doctor's instructions.

 

Interaction

With pharmaceutical: No dosage alteration is required when montelukast is co-administered with theophylline, prednisone, prednisolone, terfenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative-hypnotics, non-steroidal anti-inflammatory specialists, benzodiazepines, decongestants, verbal contraceptives, and Cytochrome P450 (CYP) protein inducers.

With nourishment and others: Bioavailability and other conditions were not altogether watched with nourishment & other conditions.

 

Contradiction

Patients who are hypersensitive to any component of Monas 10 should avoid using it.

 

Side Effects

Common: Loose bowels, fever, gastrointestinal distress, cerebral pain, queasiness, heaving, skin responses, upper respiratory tract infection.

Uncommon: Akathisia, uneasiness, arthralgia, asthenia, anomalous behavior, sadness, tipsiness, laziness, dry mouth, discharge, peevishness, discomfort, muscle complaints, edema, seizure, anomalous sensation, rest disorders.

Rare: Angioedema, concentration disabled, confusion, eosinophilic granulomatosis with polyangiitis, erythema nodosum, mental trip, hepatic disarranges, memory misfortune, palpitations, aspiratory eosinophilia, self-destructive propensities, tremor.

 

Pregnancy & Lactation

In pregnant women, there are no sufficient and well-controlled trials. Montair 10 should only be used during pregnancy if it is absolutely necessary. Montelukast is a medication that is secreted in breast milk. When Montelukast is given to a nursing woman, vigilance should be observed.

 

Precautions & Warnings

Montair 10 isn't indicated for utilizing within the inversion of bronchospasm in intense asthma assaults, counting status asthmatic. Neuropsychiatric occasions counting disturbance, threatening vibe, anxiousness, misery, confusion, unsettling influence in consideration, dream variations from the norm, mental trips, a sleeping disorder, peevishness, memory impedance, anxiety, somnambulism, self-destructive considering and behavior (counting suicide), and tremor.

 

Therapeutic Class

Antibodies to leukotriene receptors.

 

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.

 

Generic

Montelukast Sodium.

 

Related Products:

• Provair 10
• Montene 10
• M-Kast 10
• Lumona 10
• Monocast 10