Othera 20 Tablet
by ACI Limited
৳11.00
Drug International Limited
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Gastro-esophageal Reflux Disease (GERD) is treated with esomeprazole MUPS tablets (GERD).
NSAID-related gastric ulcer risk is reduced.
Eradication of Helicobacter pylori (Triple therapy).
Idiopathic hypersecretion and Zollinger-Ellison syndrome
Esomeprazole is a proton pump inhibitor that inhibits the H+/K+ ATPase in the gastric parietal cell, suppressing gastric acid secretion. The first single optical isomer of a proton pump inhibitor, esomeprazole (S-isomer of omeprazole), provides better acid control than racemic proton pump inhibitors.
Erosive esophagitis-
Maintenance of healing of erosive esophagitis-
Risk reduction in NSAID associated gastric ulcer-
H. pylori eradication (Esomeprazole MUPS tablet with 1000 mg Amoxicillin and 500 mg Clarithromycin)-
Zollinger-Ellison syndrome and idiopathic hypersecretion-
Children 1-11 years:
Children below the age of 1 year: Esomeprazole MUPS tablet is not approved for use in children younger than 1 year.
Esomeprazole MUPS tablets ought to be gulped entirety with fluid. The tablets ought to not be chewed or smashed. In case required, the tablets can moreover be scattered in half a glass of non-carbonated water (mineral water isn't appropriate). No other fluids ought to be utilized. Mix until the tablets crumble and drink the fluid with the pellets quickly or inside 30 minutes. Wash the glass with half a glass of water and drink. The pellets must not be chewed or crushed. Minimizes vacillation in plasma concentration of medicate.
Esomeprazole is broadly metabolized within the liver by CYP2C19 and CYP3A4. In vitro and in vivo thinks about have shown that Esomeprazole isn't likely to hinder CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4. No clinically important intuitive with drugs metabolized by these CYP chemicals would be anticipated. Sedate interaction thinks about have appeared that Esomeprazole does not have any clinically noteworthy intuitive with phenytoin, warfarin, quinidine, clarithromycin or amoxicillin. Esomeprazole may possibly meddled with CYP2C19, the major Esomeprazole metabolizing chemical. Co-administration of Esomeprazole 30 mg anddiazepam, a CYP2C19 substrate has brought about in a 45% diminish in clearance of diazepam. Expanded plasma levels of diazepam have been watched 12 hours after dosing and onwards. Esomeprazole restrains gastric corrosive emission. In this manner, Esomeprazole may meddled with the assimilation of drugs where gastric pH is an vital determinant of bioavailability (e.g., ketoconazole, press salts a
In patients who have a history of hypersensitivity to any of the formulations, esomeprazole is not recommended.
Caution is advised by the manufacturer. Esomeprazole or its metabolites are not known to appear in human breast milk.
If the patient has severe liver dysfunction and renal impairment, esomeprazole should be used with caution. Proton pump inhibitors, such as Esomeprazole, may slightly increase the risk of hip, wrist, and spine fractures, especially when used for more than a year.
Inhibitor of the proton pump
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.
by Healthcare Pharmaceuticals Limited
৳11.00