Ticamet 125 HFA 120 Inhaler
by Square Pharmaceuticals Limited
৳596.79
The ACME Laboratories Ltd.
Salmeterol + Fluticasone Propionate
This is indicated in the regular treatment of asthma when a combination product (long-acting 2-agonist and inhaled corticosteroid) is appropriate: patients who are not adequately controlled with inhaled corticosteroids and 'as needed' inhaled short-acting 2-agonist or patients who are already adequately controlled on both inhaled corticosteroid and long-acting 2-agonist.
Salmeterol Xinafoate is a long-acting, selective beta-2 agonist that is used to treat asthma and other types of diffuse airway obstruction. Fluticasone Propionate is a corticosteroid that primarily acts as a glucocorticoid. At normal doses, Fluticasone Propionate is said to have a topical effect on the lungs but no systemic effects.
Fluticasone Propionate improves lung function and prevents exacerbations of the illness, while Salmeterol protects against symptoms. For patients using -agonists and inhaled corticosteroids at the same time, this preparation may provide a more convenient regimen. Both medications' respective methods of action are detailed below:
Salmeterol: Salmeterol is a selective long-acting (12 hour) beta-2-adrenoceptor agonist with a long side chain which binds to the exo-site of the receptor.
Fluticasone Propionate: Fluticasone Propionate given by inhalation at recommended doses has a potent glucocorticoid anti-inflammatory action within the lungs, resulting in reduced symptoms and exacerbaions of asthma, without the adverse effects observed when corticosteroids are administered systemically.
Inhalation Aerosol:
Inhalation Powder in Capsule (For Asthma):
Inhalation Powder in Capsule (For COPD): Salmeterol 50 µg & Fluticasone 250 µg twice daily (morning and evening, approximately 12 hours apart). Rinsing the mouth after each inhalation is advised.
Inhalation Powder in Maxhaler (For Asthma): This is a moulded plastic device containing a foil strip with 60 regularly placed blisters containing pre-dispensed inhalation powder. Patients should be made aware that Maxhaler must be used daily for optimum benefit, even when asymptomatic.
Adults and Adolescents (12 years and older)-
Children (4 years and older)-
Inhalation Powder in Maxhaler (For COPD):
In patients with asthma, both non-selective and selective -blockers should be avoided unless there are compelling reasons to take them. Clinically significant medication interactions are unlikely due to the relatively low plasma concentrations attained after inhalation treatment. Co-administering Fluticasone Propionate with known strong CYP3A4 inhibitors (e.g. ketoconazole, ritonavir) should be done with caution, since there is a risk of increased systemic exposure to Fluticasone Propionate.
Patients with a history of hypersensitivity to any of the components should avoid this.
Because this product contains Salmeterol and Fluticasone Propionate, the kind and intensity of adverse events associated with each component is possible. There have been no reports of increased side effects from taking the two drugs at the same time. The following are side effects that have been linked to Salmeterol or Fluticasone Propionate.
Salmeterol: Pharmacological adverse effects of beta-2 agonist medication, including as tremor, subjective palpitations, and headache, have been recorded, but they are usually temporary and fade away with continued treatment. Arrhythmias of the heart, such as atrial fibrillation, supraventricular tachycardia, and extra systoles, can arise in vulnerable patients. Arthralgia and hypersensitivity reactions, such as rash, oedema, and angioedema, have been reported. There has been some oropharyngeal irritation reported. Muscle cramps have been reported on a few occasions.
Fluticasone propionate can cause hoarseness and mouth and throat candidiasis (thrush) in some persons. There have been reports of cutaneous hypersensitivity responses. There have been a few reports of face and oropharyngeal oedema. Gargling with water after using the Salmeterol/ Fluticasone Propionate Inhaler can help with hoarseness and candidiasis.
Drugs should only be administered during pregnancy and lactation if the predicted benefit to the mother outweighs any potential danger to the foetus or child. Salmeterol Xinafoate and Fluticasone Propionate have insufficient expertise in human pregnancy and lactation. There is no information about human breast milk.
Long-acting selective β-adrenoceptor stimulants, Respiratory corticosteroids
Even if the canister appears to be empty, it should not be punctured, broken, or incinerated. Avoid storing in direct sunlight or in a hot environment. Keep it below 30°C. Keep your distance from the eyes. Keep your distance from youngsters.
ACME Laboratories Ltd.
৳595.00