Trugain 5%

Generic

Minoxidil.

 

Indications

Minoxidil is indicated inside the treatment of androgenic alopecia in women and men and stabilization of hair loss in patients with androgenic alopecia, and also of alopecia areata.

 

Pharmacology

Minoxidil fortifies hair development by expanding oxygen, blood and supplements supply to the hair follicle by broadening blood vessels and repressing androgen hormone to influence hair follicles. Following topical application, a normal of approximately 1.4% of the entire connected measurements are retained from the ordinary intaglio scalp. Topical Minoxidil retention is expanded by expanding the measurements connected, expanding the recurrence of dosing, and diminishing the obstruction work of the stratum corneum. Serum Minoxidil levels and systemic impacts coming about from the organization of topical Minoxidil are administered by the drug’s assimilation rate through the skin. After cessation of topical dosing, roughly 95% of the systemically ingested sedate is killed within 4 days. Minoxidil and its metabolites are excreted basically within the pee.

 

Dosage & Administration

Minoxidil topical solution is for external use only and should be applied when the hair and scalp are clean and dry. Apply 1 ml (7 sprays) of Minoxidil topical solution twice daily at 12-hour intervals to the scalp, beginning at the centre of the affected area and spreading the solution out to cover the entire affected area. The total daily application dose should not exceed 2 ml.

For the best results, Minoxidil topical solution should be allowed to remain on the scalp for about 4 hours before washing. The night-time application should be done 2-4 hours before going to bed to allow the solution to dry out. Minoxidil topical solution should not be massaged into the scalp, but applied lightly. A hair dryer should not be used to speed up the drying of the solution as it may decrease the effectiveness. Minoxidil topical solution should not be mixed with any hair oil. The drug should not be used more than two times a day, or be taken orally or applied to any other part of the body to avoid the risk of adverse effects and unwanted hair growth. More frequent use or longer application time have no effect on hair growth. In case of missing any daily applications of Minoxidil topical solution, the patient should continue with the next application.

Hands should be washed immediately if Minoxidil topical solution is applied with the fingertips. Clinical experience with Minoxidil indicates that twice-daily applications for 4 months or more may be required before there is evidence of hair growth. To arrest hair fall, Minoxidil topical solution should be used for not less than 45 days. Depending upon the severity of hair loss or type and extent of baldness, particular strength of Minoxidil topical solution may be selected.

 

Interaction

There are currently no known drug interactions associated with oral medications and the use of Train.

 

Contraindications

Trugain Topical Solution is contraindicated in patients with a history of hypersensitivity to Minoxidil or any of the other ingredients in the formulations such as propylene glycol or ethanol.

 

Side Effects

Side effects are usually local and mild. Some people may experience a dry, itchy scalp and irritation.

 

Pregnancy & Lactation

There are no adequate and well-controlled studies on pregnant women. So, it is wise to use Trugain according to your doctor’s advice.

 

Precautions & Warnings

Minoxidil topical solution is more likely to cause scalp irritation. If scalp irritation continues or worsens, the use of Minoxidil topical solution should be stopped.

 

Therapeutic Class

Other preparations for the scalp.

 

Storage Conditions

Store in a cool & dry place, protected from light.

 

Pharmaceutical Name

Ziska Pharmaceuticals Ltd.