AZ-500

Generic

Azithromycin Dihydrate

 

Indications

Azithromycin is indicated for infections (caused by susceptible organisms) in lower respiratory tract infections including bronchitis and pneumonia, in upper respiratory tract infections including sinusitis and pharyngitis/tonsillitis, in otitis media, and in the skin and soft tissue infections.

 

Pharmacology

Azithromycin is acid-stable and can therefore be taken orally with no need for protection from gastric acids. It is readily absorbed; its absorption is greater on an empty stomach.

 

Dosage & Administration

500 mg once daily orally for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days. Azithromycin should be taken at least 1 hour before or 2 hours after a meal.

 

Interaction

Azithromycin absorption is reduced in presence of food and antacid. In patients receiving ergot alkaloids Azithromycin should be avoided because of the possibility of ergotism resulting from interaction of Azithromycin with the cytochrome P-450 system.

 

Contraindications

Azithromycin absorption is reduced in presence of food and antacid. In patients receiving ergot alkaloids Azithromycin should be avoided because of the possibility of ergotism resulting from interaction of Azithromycin with the cytochrome P-450 system.

 

Side Effects

Azithromycin is well tolerated with a low incidence of side effects.

 

Pregnancy & Lactation

The pregnancy Category of Azithromycin is B. Animal reproduction studies have demonstrated that Azithromycin has no evidence of harm to the fetus.

 

Precautions & Warnings

As with any antibiotic, observation for signs of superinfection with non-susceptible organisms, including fungi, is recommended. No dose adjustment is needed in patients with renal impairment.

 

Therapeutic Class

Macrolides

 

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

 

Pharmaceutical Name

Aristopharma Ltd.