Bukof 50

Indications of Bukof 50 Tablet

Butamirate Citrate is a cough suppressant that is used to treat dry (non-productive) cough. A recent viral infection could be the source of your dry cough. Butamirate Citrate is also used for cough sedation prior to and after surgical procedures and bronchoscopy in patients. It can be used to treat any type of acute cough, including whooping cough and cough caused by acute lower respiratory tract infections (tracheitis, laryngitis).

 

Pharmacology of Bukof 50 Tablet

Butamirate Citrate suppresses cough by acting directly on the cough center in the brain. Butamirate Citrate is a non-sedating, non-toxic substance that is not related to opium alkaloids chemically or pharmacologically. After oral administration, butamirate citrate is rapidly and completely absorbed. The sustained-release tablet reaches maximum concentration in 9 hours. This is a highly protein-bound organism.

 

Dosage & Administration of Bukof 50 Tablet

Use in adult:

• Butamirate Citrate 50 mg tablet: 2-3 tablets daily.
• Butamirate Citrate syrup: 15 ml 4 times daily.
• Use in children & adolescents:
• Butamirate Citrate 50 mg tablet:
• Adolescent over 12 years old: 1-2 tablets daily.

 

Interaction of Bukof 50 Tablet

The plasma level of ebastine rises when it is combined with ketoconazole or erythromycin, resulting in a longer QTc interval. Ebastine has no effect on the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam, or alcohol. The sedative effects of alcohol and diazepam may be amplified.

 

Contraindications

Intolerance to the active ingredient.

 

Side Effect of Bukof 50 Tablet

Tolerance of Butamirate Citrate is good.Adverse reactions such as rash,nausea,diarrhoea and vertigo have been observed in a few rare cases,resolving after dose reduction or treatment withdrawal.

 

Pregnancy & Lactation

During the first trimester of pregnancy, butamirate citrate should be avoided. It can be used if a doctor recommends it for the rest of the pregnancy, but only with caution. In the absence of data on the active substance's elimination in breast milk, the benefits of Butamirate Citrate administration during breast feeding should be carefully weighed against the risks of breast feeding.

 

Precautions & Warnings

Because Butamirate Citrate suppresses the cough reflex, it should not be used in conjunction with expectorants, as this may cause mucus retention in the airways, increasing the risk of bronchospasm and respiratory infections. A doctor should be consulted if the cough lasts longer than 7 days (or more than 3 days in children under the age of 12).

 

Therapeutic Class

Antihistamines that do not cause drowsiness

 

Storage Conditions

Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.

 

Pharmaceutical Name of Bukof 50 Tablet

Beacon Pharmaceuticals Ltd

 

Generic of Bukof 50 Tablet