Napro-A Plus 500 Tablet
by The ACME Laboratories Ltd.
৳15.00
Delta Pharma Limited
Naproxen Sodium + Esomeprazole Magnesium
Naproxen & Esomeprazole is indicated for the relief of signs & symptoms of-
It consists of an immediate release esomeprazole magnesium layer and an enteric coated naproxen core. Therefore, esomeprazole is first released in the stomach and then naproxen dissolves in the small intestine.
Naproxen is a non-steroidal anti-inflammatory drug with analgesic and antipyretic properties. Naproxen's mechanism of action is to inhibit prostaglandin synthesis. Esomeprazole is a proton pump inhibitor that specifically acts on the proton pump and inhibits gastric acid secretion by specifically inhibiting ATPase H + / k + in gastric parietal cells. Esomeprazole blocks final acid production. One step, thus reducing stomach acid.
Carefully consider the potential benefits & risks of this tablet & other treatment options before deciding to use this tablet. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. If a dose of Esomeprazole lower than a total daily dose of 40 mg is more appropriate, a different treatment should be considered.
Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis-
Juvenile Idiopathic Arthritis in Adolescent Patients 12 Years of Age & Older-
Do not split, chew, crush or dissolve the tablet. This tablet is to be taken at least 30 minutes before meals.
With medicine:
With food & others: Administration of Naproxen & Esomeprazole together with high-fat food in healthy volunteers does not affect the extent of absorption of naproxen but significantly prolongs tmax by 10 hours and decreases peak plasma concentration (Cmax) by about 12%.
In general, this formulation is well tolerated. The most frequent adverse reactions in clinical trials (> 5%): erosive gastritis, dyspepsia, gastritis, diarrhea, gastric ulcer, epigastric pain, nausea, etc.
Pregnancy category C. In the third trimester, it should be avoided because it can cause the ductus arteriosus to close prematurely. Due to the naproxen content, the tablet should not be used for breastfeeding mothers.
Patients with known CV disease/risk factors may be at greater risk. This tablet should be used with caution in patients with fluid retention or heart failure.
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs).
Protect from light, store bellow 30°C and keep away from children.
Delta Pharma Ltd.
by Zenith Pharmaceuticals Limited
৳10.00