Emixef 400

Indications of Emixef 400

Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:

• Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis.
• Otitis Media is caused by Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pyogenes.
• Pharyngitis and tonsillitis are caused by Streptococcus pyogenes.
• Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumonia and Haemophilus influenza.
• Uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae.

 

Pharmaceutical Name of Emixef 400

Incepta Pharmaceuticals Ltd.

 

Pharmacology

Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:

Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis. Otitis Media is caused by Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pyogenes. Pharyngitis and tonsillitis are caused by Streptococcus pyogenes. Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumonia and Haemophilus influenza. Uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae.

 

Dosage & Administration of Emixef 400

The usual course of treatment is 7 days. This may be continued for up to 14 days depending on the severity of the infection.

Adult and children over 12 years: The recommended adult dose is 200-400 mg (1 to 2 capsules) daily, given either as a single dose or in two divided doses. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of Cefixime 400 mg is recommended.

Children (6 months or older): Usually 8 mg/kg/day given as a single dose or in two divided doses or may be given as follows

• ½-1 year: 75 mg daily.
• 1-4 years: 100 mg daily.
• 5-10 years: 200 mg daily.
• 11-12 years: 300 mg daily
• In typhoid fever, the dosage should be 10 mg/kg/day for 14 days.

Children (under 6 months): The safety and efficacy of Cefixime have not been established in children aged less than 6 months.

 

Interaction of Emixef 400

Carbamazepine: Concomitant utilize lifts the carbamazepine level. Warfarin and other anticoagulants: Concomitant utilizes increments prothrombin time.

 

Contraindications

It's not recommended if you're allergic to Cefixime or other cephalosporins.

 

Side Effects of Emixef 400

The medicate is for the most part well endured. The foremost visit side impacts are the runs and stool changes; that have been more commonly related to higher measurements. Other side impacts are sickness, stomach torment, dyspepsia, heaving, tooting, headache, and discombobulation. Hypersensitivities within the frame of hasty, pruritus, urticaria, sedate fever, and arthralgia have been detailed. These responses ordinarily died down upon discontinuation of treatment.

 

Pregnancy & Lactation

However, no suitable and well-controlled studies in pregnant women have been conducted. Because animal reproduction studies do not always predict human response, this medication should only be used during pregnancy if absolutely necessary. Cefixime is not known to be excreted in human milk. When Cefixime is given to a breastfeeding mother, caution should be observed.

 

Precautions & Warnings

The sedate ought to be endorsed with caution in people with a history of gastrointestinal illness, especially colitis. The sedate ought to be given with caution in patients with stamped disabled renal work as well as those experiencing persistent mobile peritoneal dialysis and hemodialysis. Dose alteration is as it were essential in extreme renal disappointment (creatinine clearance < 20 ml/min), in that case, measurement of 200 mg once every day ought to not be surpassed.

 

Therapeutic Class

Cephalosporins of the third generation.

 

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.

 

Generic Name of Emixef 400

Cefixime Trihydrate.