Liquical

Indications of Liquical Capsule

• Calcitriol is used to treat osteoporosis after menopause.
• Renal osteodystrophy is a disease that affects the bones in the kidneys.
• Hypoparathyroidism after surgery
• Hypoparathyroidism caused by an unknown cause
• Pseudohypoparathyroidism

 

Pharmacology of Liquical Capsule

Calcitriol is one of vitamin D3's most important active metabolites. Its precursor, 25-hydroxycholecalciferol, is normally formed in the kidneys. Calcitriol aids calcium absorption in the intestine and regulates bone mineralization. Calcitriol's main function is to maintain calcium homeostasis, which includes stimulating osteoblastic activity in the skeleton.

 

Administration & Dosage of Liquical Capsule

• On the basis of serum calcium levels, the optimal daily dose of Calcitriol capsule must be carefully determined for each patient.
• Calcitriol capsules, 0.25 mcg twice daily, are recommended for postmenopausal osteoporosis.
• The initial daily dose for Renal Osteodystrophy (dialysis patients) is 0.25 mcg of Calcitriol capsule.

 

Interaction of Liquical Capsule

The risk of hypercalcemia is increased when thiazide diuretics are used together. In patients receiving digitalis treatment, the dosage of calcitriol must be determined with caution, as hypercalcemia can cause cardiac arrhythmias. Hypermagnesemia can be caused by magnesium-containing drugs (such as antacids).

 

Contraindications

Calcitriol should not be used by anyone who has a known hypersensitivity to any of its ingredients. Calcitriol is also contraindicated in all hypercalcemia-related diseases.

 

Side Effect of Liquical Capsule

Anorexia, headaches, vomiting, and constipation are all symptoms that can occur on occasion. Dystrophy, fever, polyuria, dehydration, apathy, and urinary tract infection are some of the long-term effects.

 

Pregnancy & Lactation

In humans, there is no evidence that vitamin D is teratogenic. Calcitriol should only be used during pregnancy if the benefits outweigh the risks to the baby. While mothers can breastfeed while taking Calcitriol, the mother's and infant's serum calcium levels should be monitored.

 

Precautions & Warnings

In humans, there is no evidence that vitamin D is teratogenic. Calcitriol should only be used during pregnancy if the benefits outweigh the risks to the baby. While mothers can breastfeed while taking Calcitriol, the mother's and infant's serum calcium levels should be monitored.

 

Therapeutic Class

If serum calcium levels rise to 1 mg/100 ml above normal or serum creatinine levels rise to >120 mol/l while on Calcitriol therapy, the dosage of Calcitriol should be reduced or the treatment stopped.

 

Storage Conditions

Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.

 

Pharmaceutical Name of Liquical Capsule