MaxD 20000

Indications of MaxD 20000 Capsule

Vitamin D3 insufficiency can be treated and prevented with colecalciferol (Vitamin D3). In patients with vitamin D3 deficiency, it can also be used as a supplement to particular osteoporosis treatment.

 

Pharmacology of MaxD 20000 Capsule

Colecalciferol (Vitamin D3) aids in calcium and phosphorus absorption and reabsorption. Vitamin D3 is required for optimal bone growth and density maintenance. It also helps type 2 diabetes patients maintain optimal insulin levels by reducing the severity of bacterial infection, improving lung function, reducing the risk of cancer (breast, colorectal), and preventing cancer (breast, colorectal).

 

Dosage & Administration of MaxD 20000 Capsule

For capsule: Adults:

• Treatment of Vitamin D3 deficiency: 40000 IU once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25 hydroxyvitamin D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.
• Prevention of Vitamin D3 deficiency: 20000 IU every 4 weeks. Higher doses may be required in certain situations.
• Addition to specific therapy for osteoporosis: 20000 IU once a month.

For capsule: Children (12-18 years):

• Treatment of Vitamin D3 deficiency: 20000 IU once every 2 weeks for 6 weeks.
• Prevention of Vitamin D3 deficiency: 20000 IU every 6 weeks.

For film-coated tablet: 1000 IU (1-2 tablets) daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal.

For oroflash or chewable tablets: 1000 IU to 2000 IU daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal. Place the tablet in mouth swallow after chewing.

For Syrup:
For patients with risk of Cholecalciferol deficiency:

• 0-1 yr: 400 IU/ day (2 ml)
• >1 Yr: 600 lU/ day (3 ml)

For Cholecalciferol deficient patients:

• 0-1 yr: 2000 IU/ day (+50000 IU/week ) for 6 weeks
• 1 -18 yrs: 2000 IU/ day for 6 weeks.

Injection: Prevention: 

• Infants receiving Vitamin D enriched milk: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 6 months.
• Nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months.
• Adolescents: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months during winter.
• Pregnancy: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. from the 6th or 7th month of pregnancy.
• Elderly: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 3 months. Digestive disorders, concomitant treatment with antiepileptics & other particular condition not described above; 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. or 1 ampoule (1ml) i.e. 2,00000 I.U. every 3 or 6 months.

Injection: Vitamin D deficiency:

• 1 ampoule (1ml) i.e. 2,00000 I.U. which can be repeated 1 to 6 months later. Or, as directed by the registered physician.

 

Interaction of MaxD 20000 Capsule

Phenytoin, barbiturates, glucocorticoids, certain laxatives (such as liquid paraffin), actinomycin, and imidazole antifungal medicines are all affected.

 

Contraindications

It's not recommended for people who have a history of Vitamin D3 hypersensitivity.

 

Side Effects of MaxD 20000 Capsule

Hypercalcaemia, hypercalciuria, skin rash, pruritus, urticaria, nausea, and abdominal pain are the most common adverse effects.

 

Pregnancy & Lactation

Use in Pregnancy: Vitamin D3 is essential during pregnancy. But Vitamin D3 being fat soluble, high doses can be reached in the body tissue causing overdose and toxicity. So in case of pregnancy, such high doses shall be taken only with medical supervision.

Use in Lactation: Cholecalciferol and its metabolites are excreted in breast milk. Overdose in infants induced by nursing mothers has not been observed. Yet precaution should be taken by lactating mothers before taking high doses of Vitamin D3.

 

Precautions & Warnings

In patients with compromised renal function, it should be used with caution.

 

Therapeutic Class

Vitamin D preparations, vitamin in bone development.

 

Storage Conditions

Store in a cool and dry place, protect from light. Do not freeze.

 

Pharmaceutical Name of MaxD 20000 Capsule

Ziska Pharmaceuticals Ltd

 

Generic of MaxD 20000 Capsule

Colecalciferol [Vitamin D3]