Rupa Tablet
by Aristopharma Ltd.
৳12.00
Rupadin
Beacon Pharmaceuticals Limited
1 Pc
৳12.00
1 Strip = 10 Pcs
৳120.00
1 Box = 5 Strips
৳600.00
Dosage: Rupatadine Fumarate 10mg
Form: Tablet
Generic name(s): Rupatadine Fumarate 10mg
Available (pcs): 2
Prescription required: No
Rupadin | Beacon Pharmaceuticals | Order Online - OsudPotro
Generic
Rupatadine Fumarate
Indications
Rupatadine is used to treat the symptoms of seasonal and perennial allergic rhinitis, as well as urticaria.
Pharmacology
Rupatadine is a non-sedative antagonist of histamine H1-receptors with a lengthy half-life. It also inhibits platelet activating factor (PAF) (PAF). Histamine and PAF both produce broncho constriction, which increases vascular permeability and serves as a mediator in the inflammatory process.Rupatadine has a better therapeutic impact than a single antihistamine because of its dual mechanism of action. Rupatadine also inhibits mast cell degranulation triggered by immunological and non-immune stimuli, as well as the production of cytokines, including tumor necrosis factor alpha () in human mastocytes and monocytes.
Dosage & Administration
Adults and adolescents (over 12 years): The recommended dose is 10 mg once a day. Rupatadine may be taken with or without food.
Children aged 2 to 11 year:
Children aged 2 to 11 year:
- Children weighing 25 kg or more: 1 teaspoonful (5 ml) of the oral solution once daily with or without food.
- Children weighing equal or more than 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) oral solution once daily with or without food.
Interaction
When taking Rupatadine 20 mg with ketoconazole or erythromycin at the same time, the systemic exposure is increased. When these drugs, as well as other inhibitors of the CYP3A4 isozyme, are used together, rupatadine should be used with caution. When used with statins, CNS depressants, or alcohol, rupatadine should be used with caution.
Grapefruit and grapefruit juice should not be eaten at the same time as Rupatadine.
Contraindications
Hypersensitivity to Rupatadine or to any of the excipients.
Side Effects
Asthenia, dizziness, and drowsiness are all common symptoms. Uncommon: Increased appetite, arthralgia, back pain, dizziness, constipation, cough, diarrhea, dry throat, epistaxis, fever, gastrointestinal discomfort, increased risk of infection, irritability, malaise, myalgia, nasal dryness, nausea, oropharyngeal pain, rash, thirst, vomiting, weight gain Palpitations and tachycardia are uncommon.
Pregnancy & Lactation
There are no clinical studies on the effects of Rupatadine on a pregnant woman. Rupatadine should not be used by pregnant women unless the possible benefit outweighs the risk to the baby. There is no information on whether Rupatadine is excreted in breast milk. As a result, it should not be used during lactation unless the advantages to the mother outweigh the risks.
Precautions & Warnings
Rupatadine should be taken with caution in patients who have a known QT interval prolongation, uncorrected hypokalemia, or persistent proarrhythmic circumstances including clinically severe bradycardia or acute myocardial ischemia.In senior people, rupatadine should be administered with caution (65 years and older). The use of Rupatadine 10 mg tablets in patients with compromised renal or liver function is currently not indicated due to a lack of clinical data.
Therapeutic Class
Non-sedating antihistamines
Storage Conditions
Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.
Pharmaceutical Name
Beacon Pharmaceuticals Ltd.
