Seemapyrin 75

Generic

Aspirin

Indications

The following conditions are treated with aspirin. -

• Prophylaxis against occlusive events of the arteries
• Acute ischemic stroke/TIA, myocardial infarction, myocardial re-infarction, following bypass surgery
• Headache, muscle discomfort, dysmenorrhoea, and toothache are examples of mild to moderate pain.
• Chronic pain and inflammation are common symptoms of chronic illness. Osteoarthritis.
• Cold fever and influenza are antipyretics.

Pharmacology

Aspirin prevents thrombus development on the arterial side of the circulation by lowering platelet aggregation, where thrombi are generated by platelet aggregation and anticoagulants have minimal impact. For headaches, transitory musculoskeletal pain, and dysmenorrhoea, aspirin is the analgesic of choice. It may be beneficial since it contains anti-inflammatory and antipyretic effects. Aspirin with an enteric coating lowers gastrointestinal ulcers and intestinal disruption.

Dosage and Administration

Pain, inflammatory diseases and as antipyretic: Aspirin 300 mg 1-3 tablets 6 hourly with a maximum daily dose of 4 gm.

Suspected acute coronary syndrome: 150 mg-300 mg immediately unless there are clear contraindications.

After myocardial infarction: Aspirin 150 mg daily for 1 month. Long-term use of aspirin in a dose of 75 mg daily is recommended thereafter.

Acute ischaemic stroke/Transient ischaemic stroke (TIA): The starting dose is 150 mg-300 mg daily and Aspirin 75 mg daily thereafter.

Following bypass surgery: 75 mg-300 mg daily starting 6 hours post-procedure.

Interaction

Anticoagulants, oral hypoglycemic medications, phenytoin, and sodium valporate may be enhanced by salicylates. They reduce the uricosuric action of probenecid and may make sulphonamides more toxic. In sensitive individuals, they may also cause bronchospasm or asthma episodes.

Contraindications

Seemapyrin 75 is not recommended for children under the age of 12 (Reye's syndrome), women who are breastfeeding, or those who have an active peptic ulcer. It's also not recommended for bleeding caused by haemophilia, cerebral hemorrhage, or other ulcers.

Side Effects

Seemapyrin 75 has moderate side effects such as nausea, dyspepsia, gastrointestinal ulcers, and bronchospasm when taken as directed.

Pregnancy & Lactation

It's especially crucial not to take aspirin during the last three months of pregnancy unless your doctor specifically advises you to since it can harm the unborn child or cause complications during birth. Aspirin can be found in breast milk. As a result, it should be given with caution to lactating women.

Precautions & Warnings

In asthmatics, people with uncontrolled blood pressure, and pregnant women, it should be used with caution. Patients with a nasal polyp or a nasal allergy should be treated with caution.

Therapeutic Class

Anti-platelet drugs

Storage Conditions

Pharmaceutical Name

Seema Pharmaceuticals Ltd.

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