Sodicarb 600

Indications

Management of acidosis in cardiac arrest. Management of metabolic acidosis in: Severe renal disease Uncontrolled diabetes Circulatory insufficiency from shock or dehydration Severe primary lactic acidosis Alkalinization of urine.

 

Pharmacology

Sodicarb 600 is a systemic alkylating agent. It increases plasma bicarbonate, buffers excess hydrogen ion concentration and increases blood pH, thereby reversing the clinical manifestations of acidosis. It can also be used to restore electrolyte imbalances as an adjunct to severe diarrhea where bicarbonate loss is severe.

 

Dosage & Administration

Oral: The usual dose is 300 mg to 2 grams, 1 to 4 times daily. Intravenous (Severe metabolic acidosis): Adult: By slow inj of a hypertonic solution of up to 8.4% (1000 mmol/L), or by continuous infusion of a weaker solution, usually 1.26% (150 mmol/L). For correction of acidosis during advanced cardiac life support procedures, 50 ml of an 8.4% solution may be given. Elderly: Dosage adjustments may be required. Interaction This medication has the potential to interact with many medications. Should not take any other medication within 1 to 2 hours of taking an antacid. Potentially hazardous interactions with Corticosteroids and Corticotropin, Alkalis, Calcium, Diuretics and Potassium.

 

Interaction

Sodicarb 600 has the potential to interact with many drugs, so do not take any other drugs for 1 to 2 hours after taking an antacid. Potentially dangerous interactions with cosrticosteroids, alkalis, calcium, diuretics and potassium.

 

Contraindications

This drug is contraindicated in hypoventilation, chloride depletion due to continued gastric fluid loss, metabolic and/or respiratory alkalosis, hypocalcemia, and diuretics known to cause hypokalemia. blood chlorine.

 

Side Effects

This drug is generally well tolerated. However, high doses can cause headache, nausea or irritability. If any of these effects persist or become bothersome, tell your doctor. Tell your doctor if you develop: muscle weakness, slow reflexes, confusion, swelling of the feet or ankles, black tar-like stools, coffee-colored vomiting. If you notice other effects not mentioned above, contact your doctor or pharmacist.

 

Pregnancy & Lactation

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

 

Precautions & Warnings

Pre-existing heart disease, kidney disease, liver disease, high blood pressure, any allergies. Use in Special Populations Renal Impairment: Dosage adjustments may be required. Hepatic Impairment: Dosage adjustments may be required.

 

Therapeutic Class

Intravenous fluid preparations, Urinary Alkalinizing Agent

 

Storage Conditions

Store in a cool & dry place protected from light. Keep out of reach of children. 

 

Pharmaceutical Name

Popular Pharmaceuticals Ltd

 

Generic

Sodium Bicarbonate

 

Related Products

• Sodinate 600