Sodinate 600

Generic

 

Indications

Administration of acidosis in cardiac capture. Management of metabolic acidosis in: Severe renal disease Uncontrolled diabetes Circulatory lacking from stun or dehydration Severe essential lactic acidosis Alkalinization of pee.

 

Pharmacology

Sodium bicarbonate may be a systemic alkalinizing operator. It increments plasma bicarbonate, buffers overabundance hydrogen particle concentration, and raises blood pH, subsequently turning around the clinical appearances of acidosis. It can moreover be utilized to recharge electrolyte lopsidedness as a treatment aide for extreme loose bowels where the misfortune of bicarbonate can be critical.

 

Administration & Dosage

Oral: The usual dose is 300 mg to 2 grams, 1 to 4 times daily.

Intravenous (Severe metabolic acidosis):

• Adult: By slow inj of a hypertonic solution of up to 8.4% (1000 mmol/L), or by continuous infusion of a weaker solution, usually 1.26% (150 mmol/L). For correction of acidosis during advanced cardiac life support procedures, 50 ml of an 8.4% solution may be given.
• Elderly: Dosage adjustments may be required.

 

Interaction

This medicine has the potential to associated with numerous drugs. Ought to not take any other medicine inside 1 to 2 hours of taking an stomach settling agent. Possibly unsafe intelligent with Corticosteroids and Corticotropin, Soluble bases, Calcium, Diuretics and Potassium.

 

Contraindications

This drug is contraindicated in hypoventilatory states, chloride depletion owing to continuous gastric fluid loss, metabolic and/or respiratory alkalosis, hypocalcemia and diuretics known to produce hypochloremic alkalosis.

 

Side Effect

This medicine is for the most part well endured. In any case, tall measurements may cause migraine, sickness or crabbiness. On the off chance that any of these impacts proceed or gotten to be bothersome, illuminate your specialist. Inform your specialist in case you create: muscle shortcoming, moderate reflexes, perplexity, swelling of the feet or lower legs, dark tar-like stools, coffee-ground upchuck. In the event that you take note other impacts not recorded over, contact your specialist or drug specialist.

 

Pregnancy & Lactation

Category C: Either ponders in creatures have uncovered antagonistic impacts on the hatchling (teratogenic or embryocidal or other) and there are no controlled considers in ladies or ponders in ladies and creatures are not accessible. Drugs ought to be given as it were in case the potential advantage legitimizes the potential chance to the baby.

 

Precautions & Warnings

Pre-existing heart disease, kidney disease, liver disease, high blood pressure, any allergies.

 

Therapeutic Class

Intravenous fluid preparations, Urinary Alkalinizing Agent

 

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.

 

Pharmaceutical Name