Anadol Capsule
by Square Pharmaceuticals Limited
৳8.07
TRD-Contin 50
City Overseas Ltd.
1 Pc
৳10.00
1 Strip = 10 Pcs
৳100.00
1 Box = 5 Strips
৳500.00
Dosage: Tramadol Hydrochloride 50mg
Form: Tablet
Generic name(s): Tramadol Hydrochloride 50mg
Available (pcs): 0
Prescription required: No
TRD-Contin 50mg | City Overseas Ltd | Order Online - OsudPotro
Generic
Tramadol Hydrochloride
Indications
Tramadol is a pain reliever that is used to treat moderate to severe pain. These are some of them:
- Pain after surgery
- Irritable bowel syndrome (IBS) with spastic discomfort
- Cancer-related discomfort
- Joint discomfort
- Pain in the neck and back
- Osteoporosis pain is a common symptom.
Pharmacology
Tramadol is a synthetic analgesic with a central action. It prevents neurotransmitters like serotonin and noradrenaline from being reabsorbed. As a result, it alters the transmission of pain signals by activating both descending serotonergic and noradrenergic analgesia pathways. Tramadol's analgesic effects are mediated through mu-opioid receptor activation and indirect regulation of central monoaminergic inhibitory pathways.
Dosage & Administration
Capsule or Tablet: Usual doses are 50 to 100 mg every four to six hours. For acute pain an initial dose of 100 mg is required. For chronic painful conditions an initial dose of 50 mg is recommended. Subsequent doses should be 50 to 100 mg administered 4-6 hourly. The dose level and frequency of dosing will depend on the severity of the pain.The total daily dosage by mouth should not exceed 400 mg.
Sustained Release Capsule or Tablet: One SR capsule or tablet every 12 hours, for example first one in the morning and then at the same time in the evening. The number of capsules taken at a time will depend upon severity of pain, but it should not be taken more frequently than every 12 hours.The total daily dosage by mouth should not exceed 400 mg.
Injection: A dose of 50-100 mg may be given every 4 to 6 hours by intramuscular or by intravenous infusion. For the treatment of postoperative pain,the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a maximum of 250 mg in the first hour. Thereafter, doses are 50 to 100 mg every 4 to 6 hours up to a total daily dose of 600 mg.
Suppository: Tramadol suppository should be administered rectally. For adults usual dose is 100 mg Tramadol Hydrochloride 6 hourly. In general, 400 mg Tramadol Hydrochloride (4 Tramadol suppository) per day sufficient. However, for the treatment of Cancer pain and severe pain after operations much higher daily doses can be used.
Sustained Release Capsule or Tablet: One SR capsule or tablet every 12 hours, for example first one in the morning and then at the same time in the evening. The number of capsules taken at a time will depend upon severity of pain, but it should not be taken more frequently than every 12 hours.The total daily dosage by mouth should not exceed 400 mg.
Injection: A dose of 50-100 mg may be given every 4 to 6 hours by intramuscular or by intravenous infusion. For the treatment of postoperative pain,the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a maximum of 250 mg in the first hour. Thereafter, doses are 50 to 100 mg every 4 to 6 hours up to a total daily dose of 600 mg.
Suppository: Tramadol suppository should be administered rectally. For adults usual dose is 100 mg Tramadol Hydrochloride 6 hourly. In general, 400 mg Tramadol Hydrochloride (4 Tramadol suppository) per day sufficient. However, for the treatment of Cancer pain and severe pain after operations much higher daily doses can be used.
Interaction
In general, there are no medications that interact with Tramadol that doctors should be concerned about. Monoamine oxidase (MAO) inhibitors are the only medication class that should not be used in conjunction with Tramadol. The combination of carbamazepine and Tramadol produces a substantial increase in Tramadol metabolism, necessitating an increase in Tramadol dosage.
Contraindications
People who are hypersensitive to tramadol should avoid using it. Intoxication with alcohol, hypnotics, centrally acting analgesics, opioids, or psychotropic medications is also contraindicated.
Side Effects
Dizziness/vertigo, nausea, constipation, headache, somnolence, vomiting, pruritus, CNS stimulation, asthenia, sweating, dyspepsia, dry mouth, and diarrhoea are all common adverse effects. Malaise, allergic reaction, weight loss, vasodilatation, palpitations, abdominal pain, anorexia, flatulence, GI bleeding, hepatitis, stomatitis, and other less common side effects include malaise, allergic reaction, weight loss, vasodilatation, palpitations, abdominal pain, anorexia, flatulence, GI bleeding, hepatitis, stomatitis, and others.
Pregnancy & Lactation
Tramadol has not been proven to be safe during pregnancy. It has been proven that tramadol crosses the placenta. In pregnant women, there are no appropriate and well-controlled trials. Tramadol should thus only be taken during pregnancy if the possible benefit outweighs the danger to the fetus. Because tramadol and its metabolites have been found in breast milk, Tramadol Hydrochloride should not be given to a nursing mother.
Precautions & Warnings
Respiratory depression can occur when large dosages of tramadol are combined with anesthetic medicines or alcohol. As a result, tramadol should be used with caution in individuals who are at risk of respiratory depression.
Tramadol is not advised for people who are addicted to opioids.
When treating patients who are using CNS depressants such as alcohol, opioids, anesthetic drugs, phenothiazines, tranquilizers, or sedative hypnotics, Tramadol should be used with caution and at lower doses.
Tramadol should be taken with caution in patients who are also on MAO inhibitors, as tramadol decreases the uptake of norepinephrine and serotonin.
Tramadol should be taken with caution in individuals who have high intracranial pressure or have had a brain injury, as well as those who have severe stomach pain.
Therapeutic Class
Opioid analgesics
Storage Conditions
Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.
Pharmaceutical Name
City Overseas Ltd.
