Allynol 5

Indications of Allynol 5

To play Allyl Rest Trail, you should see something like this:

• Intrauterine Growth Restriction (IUGR)
• Abortion Threat
• Recurrent Miscarriage
• Preterm Birth Threat

 

Pharmacology

Allynol 5 is a synthetic derivative of progesterone used to treat threatened pregnancy. It can prevent preterm labor and can help women give birth to a healthy newborn baby. It stimulates the secretory phase in the uterus, facilitating the development of the fertilized egg. It has a tocolytic effect; decrease the sensitivity of the uterine muscle to oxytocin. It stimulates the growth of the acinus of the mammary glands, the secretory activity of the trophoblastic cells and the growth of aldosterone of the adrenal glands. Allylestrenol also has a selective and beta effect; adrenergic. In this way, it stimulates the synthesis of placental progesterone by the body, thus increasing the secretion of placental hormones.

 

Dosage & Administration of Allynol 5

Intra Uterine Growth Retardation: 1 tablet three times a day at least two months. Dose to be reduced if symptoms improve.

Threatened abortion: 1 tablet three times daily until symptoms disappear.

Habitual abortion: 1-2 tablets daily as soon as pregnancy is diagnosed. The administration should be continued for at least one month after the end of the critical period.

Threatened premature delivery: Dosage must be determined individually. High dosages (up to 40 mg daily) have been used.

In case of a missed dose, it should be taken as soon as the patient remembers & she should continue the regular dosing schedule. A double dose is not recommended.

 

Interactions of Allynol 5

Can reduce the rate of excretion of Allylestrenol (and may cause higher serum levels):

• Benzthiazide (potentially a reduction in efficacy)
• Amphetamines
• Cefadroxil
• Amphetamines

May increase or decrease the metabolism of Allylestrenol :

• Clofazimine, Allylestrenol lines may increase when combined with Chlorpromazine
• Dalfampridine the metabolism of Allylestrenol may lower the excretion rate of Dalfampridin – which may result in higher serum levels.
• Diazepam, Allylestrenol lines can decrease when combined with Diazepam.
• There are many other types of drugs that can interact with Allylestrenol. Talk to your doctor or pharmacist for more information.

 

Contraindications

Hypersensitivity; thrombophlebitis; undiagnosed vaginal bleeding, incomplete miscarriage, hormone-dependent cancer, stroke, as a diagnostic test for pregnancy; severe liver failure.

 

Side Effects of Allynol 5

Allylestrenol treatment (especially long-term treatment) is known to cause some gastrointestinal disorders such as vomiting, nausea and sometimes abdominal discomfort.

 

Pregnancy

Allylestrenol is specially designed for use during pregnancy. The drug should be discontinued after childbirth as it may affect the infant to a small but noticeable extent.

 

Precautions

Patients with the following diseases should be careful: heart disease, congestive heart failure, sick sinus syndrome, coronary artery disease, seizures, epilepsy, kidney failure, migraine, or respiratory diseases (including asthma, emphysema), chronic bronchitis, or COPD ), lactation.

 

Therapeutic Class

Female Sex hormones

 

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

 

Pharmaceutical Name

Popular Pharmaceuticals Ltd

 

Generic Name of Allynol 5

Allylestrenol

 

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