Nidagest 5

Indications of Nidagest 5

Nidagest 5 is indicated in:

• Intrauterine Growth Retardation (IUGR) is a condition in which a woman's growth is (IUGR)
• Abortion is being threatened.
• Abortion on a regular basis
• Premature birth was a threat.

Pharmaceutical Name

Chemist Laboratories Ltd

Pharmacology

Synthetic progesterone derivative allylestrenol is used to treat threatening pregnancies. It can help women avoid early labor and give birth to a healthy newborn. It stimulates the secretory phase in the myometrium, allowing the fertilized ovum to develop. It has a tocolytic action, which means it lowers myometrium oxytocin sensitivity. It promotes the formation of mammary gland acinus, trophoblast secretory activity, and adrenal gland aldosterone production. Allylestrenol has a variety of -adrenergic effects as well. As a result, it increases the production of placental hormones by stimulating the synthesis of placental progesterone in the body.

Dosage & Administration of Nidagest 5

Intra Uterine Growth Retardation: 1 tablet three times a day at least two months. Dose to be reduced if symptoms improve.Threatened abortion: 1 tablet three times daily until symptoms disappear.

Habitual abortion: 1-2 tablets daily as soon as pregnancy is diagnosed. The administration should be continued for at least one month after the end of the critical period.

Threatened premature delivery: Dosage must be determined individually. High dosages (up to 40 mg daily) have been used.In case of a missed dose, it should be taken as soon as the patientremembers & she should continue the regular dosing schedule. A double dose is not recommended.

Contraindications

Hypersensitivity; thrombophlebitis; undiagnosed vaginal bleeding, incomplete abortion, hormone[1]dependent carcinoma, cerebral apoplexy, as a diagnostic test for pregnancy; severe hepatic impairment.

Side Effects of Nidagest 5

Treatment with Allylestrenol (especially a long term treatment) is known to cause some gastrointestinal complaints such as vomiting, nausea, and sometimes epigastric discomfort.

Pregnancy & Lactation

Allylestrenol is specifically designed to be taken during pregnancy. It should be discontinued after delivery as it may affect a nursing infant to a small but noticeable degree.

Precautions & Warnings

Patients with the following conditions should be cautious: Heart disease, congestive heart failure, sick sinus syndrome, coronary artery disease, seizures, epilepsy, renal dysfunction, migraine headaches, or breathing diseases including asthma, emphysema, chronic bronchitis, or COPD, breast-feeding.

Therapeutic Class

Female Sex hormones

Storage Conditions

Generic Name of Nidagest 5

Allylestrenol

Related Products

• Allygest 5
• Alia 5
• Prelab