Carticel TS Tablet
by Opsonin Pharma Limited
৳16.00
UniMed UniHealth Pharmaceuticals Ltd
Glucosamine Sulfate + Chondroitin
Indicated for the treatment of osteoarthritis of the knee, hip, spine, hand and other positions in the form of functional foods. It is also beneficial in rheumatoid arthritis, sports injuries, migraines, various skin problems (eg:
Glucosamine is an amino sugar naturally produced by the body and found in a number of foods. It is the most basic building block required for the biosynthesis of glycosaminoglycans (GAGs) such as hyaluronic acid, keratan sulfate, and chondroitin sulfate. GAGs bind to proteins and form proteoglycans, which make up joint cartilage. When the cartilage in the joints degrades, the process of joint degeneration develops. It also helps in the formation of ligaments, tendons, nails and many other connective tissues. When we supplement artificially synthesized glucosamine sulfate, it increases the glucosamine level in the body, thus facilitating the production and repair of cartilage. Glucosamine also activates chondrocytes to help produce GAGs and proteoglycans.
Chondroitin sulfate is a glycosaminoglycan (acid mucopolysaccharide) found in connective tissue, especially in the articular cartilage of all mammals. Chondroitin sulfate supplements work in a similar way to glucosamine sulfate, as it also provides a substrate for proteoglycans. Chondroitin also protects existing healthy cartilage from premature deterioration by preventing the enzyme MMP (Matrix metalloproteinase) from breaking down proteoglycan.
The combination of glucosamine and chondroitin sulfate shows a synergistic effect. The data confirm that this combination has been shown to be very effective in severe cases of osteoarthritis, treating both the signs and symptoms of osteoarthritis, and modulating disease progression. It prevents osteoarthritis in normal adults. In osteoarthritis pain, it was as effective as NSAIDs with significantly better clinical tolerance and compliance. It is also useful during the repair phase of musculoskeletal soft tissue injuries such as sprains or ligaments
250/200 mg tablet: 1 to 2 tablets, three times daily. Dose may be adjusted according to the response of the drug and body weight. Doses can be tapered after 60 days as per requirement of the individual and for cost convenience. Typical dosage recommendation, based on body weight is as follows-
750/600 mg tablet: 1 tablet two times daily or as directed by the physician.
There are no reports of significant drug interactions of glucosamine and chondroitin with antibiotics / antidepressants / antihypertensives / nitrates / antiarrhythmics / anxiolytics / hypoglycemic agents / drugs antitussive/asthma medication. Chondroitin may increase the anticoagulant effect of anticoagulants such as warfarin, heparin.
There are no contraindications for glucosamine and chondroitin. But proven hypersensitivity (eg, shellfish or sulfur allergy) to Glucosamine and Chondroitin is contraindicated.
Safety studies with glucosamine sulfate and chondroitin sulfate showed no demonstrable adverse effects. Rare side effects (such as mild, reversible bowel gas) were nearly the same as placebo.
Women who are or may become pregnant should not take glucosamine sulfate or chondroitin sulfate supplements. Glucosamine and chondroitin have not been studied enough to determine their effects on a developing fetus. There are no studies evaluating the use of glucosamine and chondroitin during pregnancy or breast-feeding. It should be taken with caution and medical advice during pregnancy and lactation.
Patients with diabetes should regularly monitor their blood sugar while taking glucosamine. No special studies have been performed in patients with renal or hepatic impairment. The toxicity and pharmacokinetic profiles of glucosamine and chondroitin are not limited to these patients. However, the administration of the drug to patients with severe hepatic or renal impairment should be carried out under appropriate medical supervision. Glucosamine and chondroitin supplements should not be given to children.
Stimulation of Cartilage formation
Store in a cool and dry place, protected from light.
UniMed UniHealth Pharmaceuticals Ltd
by Radiant Pharmaceuticals Limited
৳38.00