Febustat 40 Tablet
by Incepta Pharmaceuticals Ltd
৳13.00
Barif 40
Square Pharmaceuticals Limited
1 Strip = 10 Pcs
৳120.30
1 Box = 3 Strips
৳360.90
Dosage: Febuxostat 40mg
Form: Tablet
Generic name(s): Febuxostat 40mg
Available (pcs): 10
Prescription required: No
Barif Tablet 40 mg Medicine: Uses, Side Effects, Price and Dosage - osudpotro
Barif 40 mg Tablet by Square pharmaceutical Ltd is available in our Trusted medicine store. Place your order in osudpotro and get the best Price online medicine home delivery in Bangladesh.
Indications of Barif 40
Febuxostat is used to treat hyperuricemia in gout patients on a long-term basis. Febuxostat is not recommended for asymptomatic hyperuricemia therapy.
Pharmaceutical Name
Pharmacology
Febuxostat is a selective xanthine oxidase (XO) inhibitor that is non-purine. It lowers serum uric acid levels by blocking the enzyme xanthine oxidase, which produces uric acid. Xanthine oxidase converts hypoxanthine to xanthine, which is then converted to uric acid. At therapeutic dosages, Febuxostat is unlikely to inhibit other enzymes involved in purine and pyrimidine production and metabolism.
Dosage & Administration
Febuxostat is recommended at 40 mg or 80 mg once daily. The recommended starting dose of Febuxostat is 40 mg once daily. For patients who do not achieve a serum uric acid less than 6 mg /dL after 2 weeks with 40 mg, Febuxostat 80 mg is recommended. Febuxostat can be administered without regard to food or antacid use. No dose adjustment is necessary when administering Febuxostat to patients with mild to moderate renal or hepatic impairment.
Interaction of Barif 40
Febuxostat combined with azathioprine, mercaptopurine or theophylline will increase the plasma concentration of these drugs and cause serious toxicity.
Contraindications
Febuxostat is contraindicated in patients receiving azathioprine, mercaptopurine, or theophylline.
Side Effects of Barif 40
The most common adverse events associated with the use of Febuxostat may include liver function abnormalities, nausea, arthralgia, and rash.
Pregnancy & Lactation
Pregnancy Category C: There are no adequate and well-controlled studies in pregnant women. Febuxostat should be used during pregnancy only if the this drug is excreted in human milk. Caution should be exercised when Febuxostat is administered to a nursing woman.
Precautions & Warnings
Gout Flare: An increase in gout flares is frequently observed during initiation of anti-hyperuricemic agents, including Febuxostat. If a gout flare occurs during treatment, Febuxostat need not be discontinued. Prophylactic therapy (i.e., non-steroidal anti-inflammatory drug (NSAID) or colchicine upon initiation of treatment) may be beneficial for up to six months.
Cardiovascular Events: A higher rate of cardiovascular thromboembolic events was observed in patients treated with febuxostat than allopurinol in clinical trials. Monitor for signs and symptoms of MI and stroke.
Liver Enzyme Elevation: Transaminase elevations have been observed in febuxostat -treated patients. Monitor liver function tests periodically.
Therapeutic Class
Drugs used in Gout
Storage Conditions
Store in a cool and dry place. Protect from light and moisture. Keep the medicine out of the reach of children.
Generic Name of Barif 40
