Cubimox 400

Generic

Moxifloxacin Hydrochloride

Indications

Acute bacterial sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia, uncomplicated and complicated skin and skin structure infections, complicated intra-abdominal infections, and pelvic inflammatory disease are among the conditions for which moxifloxacin is prescribed.

Pharmacology

Moxifloxacin belongs to the fluoroquinolone class of antibacterial drugs, and it is a 4th generation synthetic broad spectrum antibacterial medication. It works against a wide spectrum of bacteria, including Mycoplasma pneumoniae, that are gram-positive, gram-negative, anaerobic, and atypical. Topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, and repair, are inhibited.

Dosage & Administration

Acute bacterial sinusitis: 400 mg once daily 7-10 days.
Acute bacterial exacerbation of chronic bronchitis: 400 mg once daily 5-10 days.
Community-acquired pneumonia: 400 mg once daily 7-14 days.
Uncomplicated skin and skin structure infections: 400 mg once daily 7 days.
Complicated skin and skin structure infections: 400 mg once daily 7-21 days.
Complicated intra-abdominal infections: 400 mg once daily 5-14 days.
Pelvic inflammatory disease: 400 mg once daily 14 days.

 Interaction

Moxifloxacin belongs to the fluoroquinolone class of antibacterial drugs, and it is a 4th generation synthetic broad spectrum antibacterial medication. It works against a wide spectrum of bacteria, including Mycoplasma pneumoniae, that are gram-positive, gram-negative, anaerobic, and atypical. Topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, and repair, are inhibited.

Contraindications

Patients having a history of hypersensitivity to Moxifloxacin or other quinolones should avoid it.

Side Effects

Nausea, vomiting, diarrhea, headaches, and dizziness are all common Moxifloxacin side effects.

Pregnancy & Lactation

Nausea, vomiting, diarrhea, headaches, and dizziness are all common Moxifloxacin side effects.

Precautions & Warnings

Tendinitis and tendon rupture are possible side effects of moxifloxacin. If a tendon becomes inflamed or painful, it should be stopped. It should not be used in individuals who have a known prolongation of the QT interval, hypokalemia that has not been addressed, or who are taking Class IA or Class III antiarrhythmics.

Therapeutic Class

4-Quinolone preparations

Storage Conditions

Pharmaceutical Name

ACME Laboratories Ltd.