Flexibac 10

Indications of Flexibac 10

Baclofen is used to treat spasticity caused by multiple sclerosis, flexor spasms and pain, clonus, and muscular rigidity, as well as skeletal muscle spasms caused by rheumatic disorders, spinal cord injuries, and other spinal diseases.
Cerebrovascular accidents, neoplasms, and degenerative brain disease are all possibilities.

 

Pharmacology of Flexibac 10

Baclofen inhibits monosynaptic and polysynaptic reflexes in the spinal cord by stimulating GABAB receptors, which block glutamate and aspartate release. It may also cause CNS depression by acting at intraspinal sites. Baclofen has an antinociceptive effect as well.

 

Administration & Dosage

5 mg three times a day, preferably with or after food, gradually increased to a maximum of 100 mg per day.

 

Interaction of Flexibac 10

If Baclofen is combined with central nervous system depressants, alcohol, or synthetic opiates, increased sedation may occur. Respiratory depression is a possibility as well.
Because combined treatment with Baclofen and antihypertensives is likely to cause a greater drop in blood pressure, the antihypertensive medication dosage should be adjusted accordingly.

 

Contraindications

Baclofen is not recommended for patients who are hypersensitive to any of the product's ingredients.

 

Side Effect of Flexibac 10

Transient drowsiness, daytime sedation, dizziness, weakness, and fatigue are the most common side effects of Baclofen.
Headache (ten percent), insomnia (ten percent), and euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, co-ordination disorder, tremor, rigidity, dystonia, and ataxia are all symptoms of the central nervous system.

 

Pregnancy & Lactation

Transient drowsiness, daytime sedation, dizziness, weakness, and fatigue are the most common side effects of Baclofen.
Headache (ten percent), insomnia (ten percent), and euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, co-ordination disorder, tremor, rigidity, dystonia, and ataxia are all symptoms of the central nervous system.

 

Precautions & Warnings

Patients with impaired renal function or those undergoing chronic haemodialysis should receive lower doses (approximately 5 mg per day).
Patients with spasticity, as well as psychotic disorders, schizophrenia, depressive or manic disorders, or confusional states, should be treated with caution and closely monitored, as these disorders may worsen.

 

Therapeutic Class

Skeletal Muscle Relaxants with a Central Action

 

Storage Conditions

Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.

 

Pharmaceutical Name of Flexibac 10