Lacitab 2

Generic

 

Indications

Lacidipine is shown for the treatment of hypertension either alone or in combination with other antihypertensive specialists, counting ß-blockers, diuretics, ACE-inhibitors etc.

 

Pharmacology

Lacidipine inhibits the influx of calcium into smooth muscle cells by the competitive inhibition of voltage-dependent calcium 'L' channels. This action results in the inhibition of the effects triggered by the influx of calcium into the cells, such as the activation of the contractile proteins in smooth muscle.

 

Administration & Dosage

The recommended initial dose of Lacidipine is 2 mg once daily. The dose may be increased to 4 mg and then, if necessary, to 6 mg after 3 to 4 weeks. Lacidipine should be taken preferably in the morning.

 

Interaction

Antidepressants such as SSRIs and related antidepressants should not be started for at least two weeks after stopping an MAOI. An MAOI, on the other hand, should not be started until at least one week after an SSRI or similar antidepressant has been discontinued (2 weeks in the case of paroxetine and sertraline, at least 5 weeks in the case of fluoxetine).

 

Contraindications

Hypersensitivity to any ingredient of this product, cardiogenic shock, unstable angina, aortic stenosis, avoid within 1 month of myocardial infarction, impaired left ventricular function.

 

Side Effects

Lacidipine is generally well tolerated. Some individuals may experience minor side effects like flushing, palpitation, edema, headache, dizziness, rarely gastro-intestinal disturbances, gum hyperplasia, mood disturbances, asthenia, polyuria, muscle cramps, skin rash etc.

 

Pregnancy & Lactation

Pregnancy: There are no information on the security of Lacidipine in human pregnancy. Lacidipine gives no prove of a teratogenic impact in creature study. Lactation: Drain exchange ponders in creatures have appeared that Lacidipine (or its metabolites) are likely to be excreted into breast drain. There's , be that as it may, no clinical encounter of Lacidipine in pregnancy and lactation. In like manner, Lacidipine ought to not be utilized amid pregnancy or lactation.

 

Precautions & Warnings

Cardiac conduction variations from the norm, destitute cardiac saves, hepatic impedance, pull back on the off chance that ischemic torment happens in the blink of an eye after starting treatment or in case cardiogenic stun creates, dodge grape natural product juice.

 

Therapeutic Class

Calcium-channel blockers

 

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.

 

Pharmaceutical Name