Marincal-DX

Indications of Marincal-DX Tablet

This medication is used to treat and prevent osteoporosis, osteomalacia, tetany, hypoparathyroidism, and osteogenesis disorders. Also used as a supplement in cases of insufficient calcium intake in childhood nutrition, rickets, pregnancy and lactation, and geriatric people. Other uses include pancreatitis, phosphate binder in chronic renal failure, and so on.

Pharmacology of Marincal-DX Tablet

This is a calcium and vitamin D3 supplement in which the calcium carbonate is derived from coral. The chemical structure of coral calcium carbonate is remarkably similar to the composition of human bone. Coral calcium is similar to other sources, however it is more absorbable. Vitamin D3 promotes calcium absorption from the GI tract and helps to maintain calcium homeostasis in the body.

Dosage & Administration of Marincal-DX Tablet

One tablet once or twice daily with plenty of water or as directed by the physician. Taking in full stomach ensures better absorption.

Interaction of Marincal-DX Tablet

Oral calcium can decrease the absorption of tetracycline and fluoride preparations, thus a minimum of 3 hours should elapse between taking these drugs. Thiazide diuretics decrease calcium excretion in the kidney. Vitamin D3 metabolism may be induced by phenytoin, barbiturates, and glucocorticoids. Concurrent consumption of certain foods, such as spinach, cereals, milk and its derivatives, may decrease intestinal calcium absorption.

Contraindications

Hypersensitivity to any of the components, hypocalcaemia caused by a vitamin D3 excess, hyperparathyroidism, bone metastases, severe renal insufficiency, severe hypercalciuria, renal calculi, and so on.

Side Effects of Marincal-DX Tablet

Flatulence, diarrhoea, constipation, upper Gl discomfort, allergic reactions etc are rare manifestation. Hypercalcaemia due to prolong use has rarely been reported.

Pregnancy & Lactation

vlarinCal'lDX should be given to pregnant and lactating mothers as per recommendation of physician.

Precautions & Warnings

ln mild hypercalciuria reduction of dose is sufficient to return to normal serum Calcium concentration. Plasma and serum Calcium level should be monitored in mild to moderate renal mpairment patlents and also in case of long term use. Patients with renal stone or with such previous history should be recommended to increase their fluid intake.

Therapeutic Class

Specific mineral & vitamin combined preparations

Storage Conditions

Do not store above 30° C. Keep away from light and out of the reach of children.

Pharmaceutical Name of Marincal-DX Tablet

Incepta Pharmaceuticals Ltd

Generic of Marincal-DX Tablet

Calcium Carbonate [Coral source] + Vitamin D3