Silfil 100

Generic

 

Indications

The drug sildenafil is used to treat erectile dysfunction.

 

Pharmacology

Sildenafil could be a specific inhibitor of cyclic Guanosine Monophosphate (cGMP)-specific phosphodiesterase sort 5 (PDE5) utilized for treatment of erectile brokenness. Danafil (Sildenafil) improves the impact of nitric oxide (NO) by hindering phosphodiesterase sort 5 (PDE5), which is dependable for corruption of cGMP within the corpus cavernosum that comes about in smooth muscle unwinding and influx of blood to the corpus cavernosum.

                                                                                                          

Dosage

The recommended dose of Sildenafil is 50 mg taken approximately 1 hour before sexual activity. However, Sildenafil may be taken anywhere from half an hour to 4 hours before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.

 

Administration

Sildenafil may takes longer time to work if you take it with a heavy meal.

 

Interaction

When Sildenafil is taken with organic nitrates for angina, it can cause hypotension. Cimetidine, a drug used to treat gastric ulcers, as well as some antibiotics like Erythromycin and Rifampicin, and protease inhibitors like Ritonavir and Saquinavir used to treat HIV infection, may raise Sildenafil levels in the blood.

 

Contraindications

Any component of sildenafil is contraindicated in patients who are hypersensitive to it. Because sildenafil enhances the hypotensive effects of nitrates, it is not recommended for patients who are taking organic nitrates on a regular or intermittent basis..

 

Side Effects

Headache, flushing, dyspepsia, nasal congestion, urinary tract infection, abnormal vision, diarrhea, dizziness, and rash are all side effects of Sildenafil.

 

Pregnancy & Lactation

Category B pregnancy. Sildenafil has not been studied in pregnant women in a sufficient and well-controlled manner. Sildenafil is not recommended for women. Sildenafil has been shown to be teratogenic and embryotoxic in animal studies.

 

Precautions & Warnings

Caution ought to be worked out in the event that patients have any sensitivities to any other medications or any other substances such as nourishments, additives or colors, heart or blood vessel issues, sudden misfortune of visual perception in one or both eyes.Caution ought to be taken in case patients have any of the taking after restorative conditions such as diabetes, kidney or liver issues, leukemia, different myeloma, any illness or distortion of penis, any dying clutter such as hemophilia, stomach ulcer, sickle cell frailty, color vision issues, sudden diminish or misfortune of hearing or accepting any other treatment for weakness.

 

Therapeutic Class

Drugs for Erectile Dysfunction

 

Storage Conditions

Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.

 

Pharmaceutical Name

Organic Health Care