Virobion

Generic

Vitamin B1, B6 & B12

Indications

Vitamins B1, B6 and B12 are suitable for the treatment of vitamin B1, B6 and B12 deficiencies. It is also suitable for the supportive treatment of neuritis and inflammatory diseases of neurons, such as

• Diabetic neuropathy
• Peripheral neuralgin
• Lumbago
• Myalgia
• Optic neuritis
• Sciatica
• Facial neuralgia
• Intercostal neuralgia
• Spinal pain.

Pharmacology

Vitamin B1 converts carbohydrates, fatty acids and amino acids into energy, promotes nerve health, improves mood, and strengthens the heart. Vitamin B6 forms red blood cells, helps cells produce protein, and produces neurotransmitters, for example. Serotonin and the release of stored forms of energy help prevent CVS disease and stroke, and help relieve depression and insomnia. Vitamin B12 is essential for cell replication and for the production of red blood cells. It can prevent anemia, help prevent depression, relieve nerve pain, numbness, tingling and reduce the risk of heart disease. 
 

Vitamin ingredients are well absorbed orally. It is widely distributed in most tissues and occurs in breast milk. In the cell, thiamine exists primarily in the form of diphosphate. Thiamine is not stored in the body at any noticeable level, and the amount that exceeds the body's needs will be excreted in the urine as unchanged thiamine or metabolites. After oral administration, pyridoxine, pyridoxal, and pyridoxamine are readily absorbed from the gastrointestinal tract and converted to the active forms of pyridoxal phosphate and pyridoxamine phosphate. They are mainly stored in the liver, where they are oxidized to 4 pyridoxine and other inactive metabolites, which are excreted in the urine. As the dose increases, the amount of urine excreted in the original form increases proportionally.

Dosage & Administration

Tablet: 1-3 Tablets per day or as advised by the physician.

Injection:

• In severe (acute) cases: 1 injection daily until the acute symptoms subside or taken as advised by the physician.
• In mild cases: 1 injection 2-3 times per week. Ampoules are preferably injected intramuscularly.

Use in children: There is no information on the use of this drug in children.

Contraindications

Vitamin B1, vitamin B6 and vitamin B12 are contraindicated in patients receiving treatment with levodopa and in patients allergic to any ingredient in the preparation.

Side Effects

It is generally well tolerated, but in some cases allergic reactions can be seen.

Pregnancy & Lactation

The oral tablet form is recommended, but due to the presence of benzyl alcohol, injection is not recommended during pregnancy and while breastfeeding.

Precautions & Warnings

Patients with subacute spinal cord degeneration should not use cyanocobalamin. Cyanocobalamin is not a suitable form of vitamin B12 and is used to treat optic neuropathy associated with elevated plasma levels of cyanocobalamin.

Therapeutic Class

Specific combined vitamin preparations

Storage Conditions

Pharmaceutical Name

Virgo Pharmaceuticals Ltd.