Cildip 5 Tablet
by Opsonin Pharma Limited
৳8.00
Popular Pharmaceuticals Ltd.
Cilnivas 5 mg Tablet is used in the treatment of Cilnivas is indicated for the management of hypertension in adults.
Cilnivas is indicated for the management of hypertension in adults.
Cilnidipine is a novel 4th generation dihydropyridine calcium-channel blocker (CCB). It inhibits cellular influx of calcium by blocking both of L-type voltage-gated calcium channels in vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals and causes vasodilation of peripheral resistance vessels and coronary arteries. It has greater selectivity for vascular smooth muscle.The blockade of N-type calcium channels affects predominantly peripheral nerve endings of sympathetic neurons, thereby dilating blood vessel by lowering plasma catecholamine levels. Thus simultaneous blockade of the L-type & N-type calcium channels result in significant reduction of the blood pressure without causing reflex tachycardia.
Adults: 5-10 mg once daily after breakfast. Maximum dose: 20 mg once daily. The safety of Cilnidipine in pediatric patients has not been established.
Use in the elderly: Since the elderly may be more susceptible to hypotension, therapy should be initiated with the lowest possible dose (5 mg).
Cilnivas is contraindicated in patients with known hypersensitivity to Cilnidipine, cardiogenic shock, recent
myocardial infarction or acute unstable angina, severe aortic stenosis.
The most common side effects of Cilnidipine are: Dizziness; flushing; headache; hypotension; peripheral edema; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression.
Cilnidipine should not be administered in pregnant woman or woman having possibilities of being pregnant. It is also advisable to avoid the administration of Cilnidipine to nursing mothers. However, if the administration is indispensable, the patient should be instructed to discontinue lactation.
Hypotension, poor cardiac reserve, heart failure. Sudden withdrawal may exacerbate angina. Discontinue in patients who experience ischemic pain following administration.
Calcium-channel blockers
Keep out of direct sunlight and store in a cool, dry location. Keep out of children's reach.
by ACI Limited
৳10.00