Cildip 5 Tablet
by Opsonin Pharma Limited
৳8.00
LNC 5
Square Pharmaceuticals Limited
Dosage: Cilnidipine 5mg
Form: Tablet Pot
Generic name(s): Cilnidipine 5mg
Available (pcs): 0
Prescription required: No
LNC 5 | Square Pharmaceuticals Limited | Online Pharmacy | Ordering Medicines Online In Dhaka | OsudPotro
Indications of LNC 5
Pharmacology
Cilnidipine binds to the dihydropyridine binding sites of the L-type voltage dependent calcium channel and inhibits Ca2+ influx across the cell membranes of vascular smooth muscle cells via this channel, consequently vascular smooth muscle is relaxed, causing vasodilation. Cilnidipine inhibits Ca2+ influx via N-type voltage dependent calcium channels in the sympathetic nerve cell membrane. Consequently, release of norepinephrine from sympathetic nerve terminals are inhibited. Cilnidipine is considered to suppress the reflex increase in heart rate after blood pressure reduction.
Dosage & Administration
Adults: 5-10 mg once daily after breakfast. Maximum dose: 20 mg once daily. The safety of Cilnidipine in pediatric patients has not been established.
Use in the elderly: Since the elderly may be more susceptible to hypotension, therapy should be initiated with the lowest possible dose (5 mg).
Interaction of LNC 5
Other anti-hypertensive, antipsychotics that cause hypotension, quinidine, carbamazepine, phenytoin, rifampicin, cimetidine, erythromycin.
Contraindications
Cilnidipine is contraindicated in patients with known sensitivity to Cilnidipine or any of the excipients or patients having cardiogenic shock, recent MI or acute unstable angina and severe aortic stenosis.
Side Effects of LNC 5
The most common side effects of Cilnidipine are: Dizziness; flushing; headache; hypotension; peripheral edema; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression.
Pregnancy & Lactation
Cilnidipine should not be administered in pregnant woman or woman having possibilities of being pregnant. It is also advisable to avoid the administration of Cilnidipine to nursing mothers. However, if the administration is indispensable, the patient should be instructed to discontinue lactation.
Precautions & Warnings
Cilnidipine should be administered with care in the following patients: patients with serious hepatic dysfunction, patients with a history of serious adverse reactions to calcium antagonists. During the discontinuation, the dosage should be gradually decreased under close observation.
Therapeutic Class
Calcium-channel blockers
Storage Conditions
Store below 30°C, protect from light and moisture. Keep out of reach of children.
