Ebamine 10

Indications of Ebamine 10

Ebastine is indicated for the symptomatic treatment of:

• Seasonal and Perennial Allergic Rhinitis.
• Chronic Idiopathic Urticaria.

 

Pharmaceutical Name

Ibn Sina Pharmaceuticals Ltd.

 

Pharmacology

Ebastine is a long-acting and selective antagonist of the H1-histamine receptor. The blockage of peripheral receptors stays stable after repeated treatment. Following oral administration, ebastine is readily absorbed and undergoes significant first-pass metabolism. Carebastine, a pharmacologically active acid metabolite, is almost completely transformed from ebastine..

 

Dosage & Administration

Tablet:

• Adults (more than 12 years of age): 10 mg (one tablet) once daily.
• Children (6-12 years of age): 5 mg (half tablet) once daily.

Syrup:

• Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis).
• Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis).

Ebastine may be taken with or without food.

 

Interaction of Ebamine 10

When ebastine is used with either ketoconazole or erythromycin, the plasma level of ebastine rises, resulting in a longer QTc interval. Ebastine had no effect on theophylline, warfarin, cimetidine, diazepam, or alcohol pharmacokinetics. Alcohol plus diazepam's sedative effects may be amplified.

 

Contraindications

Patients who have previously tested positive for Ebastine or any of its components.

 

Side Effects of Ebamine 10

The most common side-effects are headache, dry mouth and drowsiness. Less commonly reported side effects include abdominal pain, dyspepsia, nausea and insomnia.

 

Therapeutic Class

Non-sedating antihistamines

 

Storage Conditions

Store below 30°C at a cool and dry place, away from light. Keep out of reach of children.

 

Generic of Ebamine 10

Ebastine