Fexo 120 Tablet
by Square Pharmaceuticals Limited
৳9.00
Radiant Pharmaceuticals Limited
Fexofenadine Hydrochloride
Fexofenadine Hydrochloride is intended for the treatment of symptoms associated with seasonal allergic rhinitis in adults and children. It is also approved for the treatment of simple cutaneous symptoms of chronic idiopathic urticaria.
Fexofenadine Hydrochloride is an antihistamine with selective peripheral H1-receptor antagonistic activity.Fexofenadine is rapidly absorbed after oral doses with peak plasma concentrations being reached in 2-3 hours. It is about 60% to 70% bound to plasma proteins. About 5% of the total doses is metabolized, mostly by the intestinal mucosa, with only 0.5% to 1.5% of the dose undergoing hepatic biotransformation by the cyto-chrome P450 system. Elimination half-life of 14 hours has been reported although this may be prolonged in patients with renal impairment. Excretion is mainly in the faeces with only 10% being present
in the urine. Fexofenadine does not appear to cross the blood-brain barrier.
Seasonal Allergic Rhinitis-
Adults and children 12 years and older:
Children from 6 to 11 years:
Children from 2 to 11 years
Chronic Idiopathic Urticaria-
Adults and children 12 years and older:
Children from 6 to 11 years:
Children from 6 months to less than 2 years:
Children from 2 to 11 years:
Plasma concentrations of Fexofenadine have been increased when given with Erythromycin or Ketoconazole. Antacid containing Aluminium and Magnesium Hydroxide reduces the absorption of Fexofenadine. Fruit juices including grapesfruit may reduce the bioavailability of Fexofenadine and use together should be avoided.
Fexofenadine is contraindicated in patients with known hypersensitivity to any of the ingredients.
Headache, tiredness, sleepiness, nausea, dry mouth, and gastrointestinal problems are common adverse effects.
There are no adequate and well controlled studies in pregnant women. Fexofenadine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Fexofenadine is excreted in human milk or not. Caution should be exercised when Fexofenadine is administered to a nursing woman.
Patients over the age of 65 and those with impaired renal function should be treated with caution.
Antihistamines that do not sedate
Store in a cool & dry place, protect from light & moisture. Keep out of reach of children.
Radiant Pharmaceuticals Ltd.
by Opsonin Pharma Limited
৳9.00