Fixal 120

Indications of Fixal 120

Fexofenadine Hydrochloride is used to treat the symptoms of seasonal allergic rhinitis in adults and children. It's also used to treat simple cutaneous symptoms of chronic idiopathic urticaria.

 

Generic of Fixal 120

Fexofenadine Hydrochloride

 

Pharmacology

Fexofenadine Hydrochloride is an antihistamine having H1-receptor antagonist action in the peripheral nervous system. After oral administration, it is quickly absorbed and reaches maximal plasma concentration in 2-3 hours. It appears that it does not pass the blood-brain barrier.

 

Dosage & Administration

Seasonal Allergic Rhinitis-

Adults and children 12 years and older:

• Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
• In case of impaired renal function: 60 mg once daily

Children from 6 to 11 years:

• Tablet: 30 mg twice daily or 60 mg once daily
• In case of impaired renal function: 30 mg once daily

Children from 2 to 11 years:

• Suspension: 30 mg or 5 ml twice daily
• In case of impaired renal function: 30 mg or 5 ml once daily

Chronic Idiopathic Urticaria-

Adults and children 12 years and older:

• Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
• In case of impaired renal function: 60 mg once daily

Children from 6 to 11 years:

• Tablet: 30 mg twice daily or 60 mg once daily
• In case of impaired renal function: 30 mg once daily

Children from 6 months to less than 2 years:

• Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily
• In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily

Children from 2 to 11 years:

• Suspension: 30 mg or 5 ml (1 tsp) twice daily
• In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily

 

Interaction of Fixal 120

When combined with erythromycin or ketoconazole, the plasma concentration of Fexofenadine Hydrochloride increased. Fexofenadine Hydrochloride absorption is reduced by antacids containing aluminium and magnesium hydroxide.

 

Contraindications

Patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its components should not use it.

 

Side Effects of Fixal 120

Headache, tiredness, sleepiness, nausea, dry mouth, and gastrointestinal problems are common adverse effects.

 

Pregnancy & Lactation

Fexofenadine Hydrochloride is classified as Category C by the US Food and Drug Administration. As a result, unless the potential advantages to the other outweigh the potential hazards to the fetus, Fexofenadine Hydrochloride should be avoided during pregnancy and breastfeeding.

 

Precautions & Warnings

Patients over the age of 65 and those with impaired renal function should be treated with caution.

 

Therapeutic Class

Non-sedating antihistamines

 

Storage Conditions

Keep away from light and heat in a dry area. Keep out of children's reach.

 

Pharmaceutical Name of Fixal 120

Opsonin Pharma Limited