Fexomin 120

Generic

Fexofenadine Hydrochloride

 

Indications

Fexofenadine Hydrochloride is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children. It is also indicated for the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.

 

Pharmacology

Fexofenadine Hydrochloride is an antihistamine with selective peripheral H1-receptor antagonist activity. It is rapidly absorbed after oral administration and peak plasma concentration is reached in 2-3 hours. It does not appear to cross the blood brain barrier.

 

Dosage & Administration

Seasonal Allergic Rhinitis- Adults and children 12 years and older:

Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily

In case of impaired renal function: 60 mg once daily

Children from 6 to 11 years: Tablet: 30 mg twice daily or 60 mg once daily

In case of impaired renal function: 30 mg once daily Children from 2 to 11 years

Suspension: 30 mg or 5 ml twice daily

In case of impaired renal function: 30 mg or 5 ml once daily

Chronic Idiopathic Urticaria- Adults and children 12 years and older: Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily

In case of impaired renal function: 60 mg once daily

Children from 6 to 11 years: Tablet: 30 mg twice daily or 60 mg once daily

In case of impaired renal function: 30 mg once daily

Children from 6 months to less than 2 years: Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily

In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily

Children from 2 to 11 years:

Suspension: 30 mg or 5 ml (1 tsp) twice daily In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily

 

Interaction

Plasma concentration of Fexomin have been increased when given with erythromycin or ketoconazole. Aluminium and magnesium hydroxide containing antacid reduces the absorption of Fexofenadine Hydrochloride.

 

Contraindications

Contraindicated in patients with known hypersensitivity to Fexomin or any of its ingredients.

 

Side Effects

Common side effects are headache, fatigue, drowsiness, nausea, dry mouth and gastrointestinal disturbances.

 

Pregnancy & Lactation

US FDA pregnancy category of Fexomin is C. So, Fexofenadine Hydrochloride should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.

 

Precautions & Warnings

Caution should be exercised in elderly patient and patient with decreased renal function. Overdose Effects In case of an overdose, standard measures to remove any unabsorbed drug should be employed. Symptomatic and supportive treatment is recommended. There has been no reported case of an acute overdose of Fexomin.

 

Therapeutic Class

Non-sedating antihistamines

 

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

 

Pharmaceutical Name

Ibn Sina Pharmaceuticals Ltd.