Sensit

Generic

Flupentixol + Melitracen

Indications

Flupentixol and Melitracen tablets are used in the following situations:

• Anxiety
• Depression
• Apathy
• Depression caused by psychological factors.
• Neuroses of depression.
• Depression that isn't visible.
• Anxiety and apathy accompany psychosomatic affections.
• Depressions associated with menopause.
• In drinkers and drug users, dysphoria and sadness are common.

Pharmacology

This comprises of two well-known and well-proven compounds: flupentixol, a neuroleptic with depressive and anxiolytic effects at modest dosages, and melitracen, a bipolar thymoleptic with activating qualities in low doses. When the chemicals are combined, they form an antidepressant, anxiolytic, and activating formulation. Flupentixol and melitracen attain their maximum blood concentrations in around 4 hours after oral treatment. Flupentixol has a biological half-life of 35 hours while melitracen has a biological half-life of 19 hours.The combination of flupentixol and melitracen does not seem to influence the pharmacokinetic properties of the individual compounds.

Dosage & Administration

Adults: Usually 2 tablets orally daily in the morning and noon. In severe cases, the morning dose may be increased to 2 tablets.

Elderly patients: 1 tablet in the morning.

Maintenance dose: Usually 1 tablet orally in the morning. In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.

Interaction

Alcohol, barbiturates, and other CNS depressants may be enhanced by this pill. Hypertensive crises may occur if MAO inhibitors are used at the same time. The antihypertensive impact of guanethidine and similar acting substances is reduced by neuroleptics and thymoleptics, whereas the effects of adrenaline and noradrenaline are enhanced by thymoleptics.

Contraindications

• After a myocardial infarction, the immediate recovery period begins.
• Bundle-branch conduction defects.
• Narrow-angle glaucoma that has not been treated.
• Intoxication with alcohol, barbiturates, or opiates.
• Patients who have received an MAO inhibitor during the last two weeks should not take this pill.
• Because of its stimulating impact, it is not advised for excitable or hyperactive patients, since it may exaggerate these traits.

Side Effect

Side effects are uncommon at recommended dosages. It's possible that you're experiencing temporary restlessness and sleeplessness.

Pregnancy & Lactation

This pill should not be taken when pregnant or breastfeeding.

Precautions & Warnings

If the patient has previously been given tranquilizers having sedative effects, they should be progressively tapered down.

Therapeutic Class

Combined anxiolytics & anti-depressant drugs

Storage Conditions

Store in a dry location at a temperature of not more than 30°C. Protect yourself from the sun. Keep out of children's reach.

Pharmaceutical Name

Eskayef Pharmaceuticals Ltd.