Omidon 10 Tablet
by Incepta Pharmaceuticals Ltd
৳3.50
Motigut
Square Pharmaceuticals Limited
1 Pc
৳4.00
1 Strip = 10 Pcs
৳40.00
1 Box = 10 Strips
৳400.00
Dosage: Domperidone Maleate 10mg
Form: Tablet
Generic name(s): Domperidone Maleate 10mg
Available (pcs): 96
Prescription required: No
Motigut | Motigut 10 mg Tablet | Domperidone Maleate | Online Pharmacy - OsudPotro
Motigut 10 mg Tablet by Square Pharmaceuticals Ltd is available in our online pharmacy. Place your order in Osudpotro and get online medicine home delivery.
Generic
Indications
Dyspeptic side effect complex, regularly related with deferred gastric purging, gastroesophageal reflux, and esophagitis:
- Epigastric sense of completion, the feeling of stomach distension, upper stomach pain
- Eructation, tooting, early satiety
- Nausea and vomiting
- Heartburn with or without regurgitations of gastric substance within the mouth Non-ulcer dyspepsia
Acute queasiness and spewing of the useful, natural, irresistible, dietetic beginning or actuated by radiotherapy or sedate treatment or initiated in migraine.
Parkinson's illness: In dopamine-agonist initiated sickness and vomiting. Radiological ponders Speeding barium travel in follow-through radiological studies.
Pharmacology
Motigut could be a dopamine adversary that principally squares the dopamine receptors found within the ChemoreceptorTrigger Zone (CTZ) and stomach. Its gastroprokinetic activity is based on its blocking impact of dopamine receptors that have an impact on the motility of the gastrointestinal tract. Due to its powerless infiltration over the blood-brain barrier, Domperidone has nearly no impact on the dopaminergic receptors within the brain, subsequently, barring psychotropic and neurologic side impacts. Domperidone reestablishes typical motility and tone of the upper gastrointestinal tract, encourages gastric purging, improves antral and duodenal peristalsis and controls withdrawal of the pylorus. Domperidone moreover increments esophageal peristalsis and lower esophageal sphincter weight, and hence avoids spewing forth of gastric substance.
Dosage & Administration
Motigut ought to be taken 15-30 minutes sometime recently suppers and, in case vital, sometime recently retiring.
The regular suggested verbal dosage of Domperidone is as follows:
- Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension), each 6-8 hours day by day. The most extreme measurements of Domperidone is 80 mg daily.
- Children: 2-4 ml suspension/10 kg body weight or 0.4-0.8 ml pediatric drops/10 kg body weight, each 6-8 hours daily.
In dyspeptic symptoms:
- Adults: 10-20 mg (1-2 tablets or 10-20 ml suspension), each 6-8 hours daily.
- Children: 0.2-0.4 mg/kg (2-4 ml suspension/10 kg or 0.4-0.8 ml pediatric drops/10 kg) body weight, each 6-8 hours daily.
In intense and sub-acute conditions (primarily in intense sickness and vomiting):
- Adults: 20 mg (2 tablets or 20 ml suspension), each 6-8 hours daily
- Children: 0.2-0.4 mg/kg (2-4 ml suspension/10 kg or 0.4-0.8 ml pediatric drops/10 kg) body weight, each 6-8 hours every day. (In intense queasiness and heaving most extreme period of treatment is 12 weeks).
By rectum in suppositories:
- Adults (counting elderly): 30-60 mg each 4-8 hours.
- Children: The most extreme day-by-day measurements rectally in children's is 30 mg for those weighing 10 to 25 kg. The dosage may be partitioned all through the day on the off chance that vital. The most extreme period of treatment is 12 weeks.
Interaction
Motigut may decrease the hazard of hypoprolactemic impact of bromocriptine. The activity of Motigut on Gl work may be antagonized by antimuscarinics and opoid analgesics. Care ought to be worked out when domperidone is managed in combination with MAO (monoamine oxidase) inhibitors.
Contraindications
Motigut is contraindicated to patients having known extreme touchiness to this sedate and within the case of neonates. Domperidone ought to not be used whenever gastrointestinal incitement can be perilous i.e., gastrointestinal hemorrhage, mechanical hindrance or puncturing. Too contraindicated in patients with prolactin discharging pituitary tumor (prolactinoma).
Side Effects
Motigut may create hyperprolactinemia (1.3%). This may result in galactorrhea, breast broadening, and soreness, and diminished charisma. Dry mouth (1%), thirst, cerebral pain (1.2%), anxiety, tiredness (0.4%), runs (0.2%), skin hasty, and tingling (0.1%) may happen amid treatment with domperidone. Extra-pyramidal responses are seen in 0.05% of patients in clinical thinks.
Pregnancy & Lactation
The security of domperidone has not been demonstrated and it is in this manner not suggested amid pregnancy. The creature thinks about have not illustrated the teratogenic impact within the embryo. Motigut may accelerate galactorrhea and move forward post-natal lactation. It is emitted in breast drain but in exceptionally little amounts deficiently to be considered destructive.
Precautions & Warnings
Motigut ought to be utilized with outright caution within the case of children since there may be an expanded chance of extrapyramidal responses in youthful children since of a not completely created blood-brain boundary. Since domperidone is exceedingly metabolized in the liver, it ought to be utilized with caution in understanding hepatic disability.
Therapeutic Class
Motility Stimulants, Motility stimulants/Dopamine opponent, Prokinetic drugs
Storage Conditions
Store below 30°C, Secured from light & dampness. Keep out of children's reach.
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