Rejoin-D

Generic

Glucosamine Sulfate + Diacerein

Indications

This tablet is indicated in-

• Osteoarthritis
• Rheumatoid arthritis
• Bone and Joint injuries

Pharmacology

Glucosamine (2-amino-2-deoxy-alpha-D-glucose) is a naturally occurring amino sugar that is created by the body and found in a variety of meals. It's the most basic building component for glycosaminoglycans (GAGs) like Hyaluronic Acid, Keratan Sulfate, and Chondroitin Sulfate production. GAGs bond to proteins to create proteoglycans, which are an important component of articular cartilage. Osteoarthritis develops when cartilage in a joint deteriorates. Glucosamine (2-amino-2-deoxy-alpha-D-glucose) is a naturally occurring amino sugar that is created by the body and found in a variety of meals. It's the most basic building component for glycosaminoglycans (GAGs) like Hyaluronic Acid, Keratan Sulfate, and Chondroitin Sulfate production. GAGs bond to proteins to create proteoglycans, which are an important component of articular cartilage. Osteoarthritis develops when cartilage in a joint deteriorates.

Diacerein is a drug that is used to treat osteoarthritis. It also possesses anti-inflammatory, anti-pyretic, and analgesic properties. It reduces the production of InterLeukin-1 (IL-1), the major cytokine involved in cartilage breakdown, in vitro. It has been proven to have a disease-modifying impact in laboratory models of osteoarthritis and in human subjects with finger joint and knee osteoarthritis due to its particular mode of action.

Diacerein is a drug that is used to treat osteoarthritis. It also possesses anti-inflammatory, anti-pyretic, and analgesic properties. It reduces the production of InterLeukin-1 (IL-1), the major cytokine involved in cartilage breakdown, in vitro. It has been proven to have a disease-modifying impact in laboratory models of osteoarthritis and in human subjects with finger joint and knee osteoarthritis due to its particular mode of action.

Dosage and Administration

Use in adults: One tablet twice daily with food.

Use in children and adolescents: The safety and effectiveness of children and adolescents under the age of 18 years have not been established.

Interaction

Decrease absorption of Diacerein with aluminium and/ or magnesium hydroxide antacids. Increase risk of diarrhea with laxatives or antibiotics.

Contraindications

Contraindicated for those who shows hypersensitivity to Glucosamine or Diacerein.

Side Effects

No serious adverse effect has been reported. Nausea, vomiting, diarrhea, epigastria pain, headache, skin rashes & intense yellow coloring of urine may be occurred.

Pregnancy & Lactation

This tablet is contraindicated during pregnancy and breastfeeding.

Precautions & Warnings

In the case of individuals who are allergic to Glucosamine or Diacerein, caution should be exercised when delivering this tablet.

Therapeutic Class

Stimulation of Cartilage formation

Storage Conditions

Store in cool & dry place below 30ºC, protect from light & moisture. Keep out of reach of children.

Pharmaceutical Name

Aristopharma Ltd.